308 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
251 5PLE Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.81 SHOW
252 5PJT Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.81 SHOW
253 5PLP Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.81 SHOW
254 5PNV Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.81 SHOW
255 5PJQ Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.81 SHOW
256 5PKW Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.81 SHOW
257 5PJ3 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.81 SHOW
258 6F5T Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-oxidanyl-4-(2~{H}-1,2,3,4-tetrazol-5-yl)pyridine-2-carboxamide CQK 0.81 SHOW
259 6H0W Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-phenyl-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHW 0.81 SHOW
260 6H4P Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQ5 0.8 SHOW
261 5FZH Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) (3R)-5-fluoro-3-hydroxy-1,3-dihydro-2H-indol-2-one 0TI 0.8 SHOW
262 4D6Q Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) PYRIDINE-2,4-DICARBOXYLIC ACID PD2 0.79 SHOW
263 3DXU Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.78 SHOW
264 6H0Z Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-[(~{E})-(4-bromophenyl)methylideneamino]-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanamide FHQ 0.77 SHOW
265 6H10 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-[(~{E})-(4-methylphenyl)methylideneamino]-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanamide FJ8 0.77 SHOW
266 5PN4 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
267 5F5A Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-[(furan-2-ylmethylamino)methyl]pyridine-4-carboxylic acid 5V0 0.76 SHOW
268 6H4X Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(4-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FNQ 0.76 SHOW
269 6H4Y Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-(2-morpholin-4-ylethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FO8 0.75 SHOW
270 6F5R Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-(3-oxidanylpropylamino)pyridine-4-carboxylic acid CQZ 0.74 SHOW
271 6H0Y Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-(4-methoxyphenyl)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHZ 0.73 SHOW
272 5FYU Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) (3R)-3-azanyl-4-methyl-1,3-dihydroindol-2-one BY4 0.73 SHOW
273 5F5C Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 8-[[(phenylmethyl)amino]methyl]-1~{H}-pyrido[3,4-d]pyrimidin-4-one 5V3 0.73 SHOW
274 6ETS Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoylamino]azanium I1L 0.71 SHOW
275 6EIU Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 8-oxidanyl-6-phenyl-7-propan-2-yl-imidazo[1,2-b]pyridazine-3-carbonitrile B6T 0.71 SHOW
276 5IVE Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile 6E8 0.71 SHOW
277 6F5S Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-(3-morpholin-4-ylpropyl)-4-(2~{H}-1,2,3,4-tetrazol-5-yl)pyridine-2-carboxamide CQT 0.7 SHOW
278 6H4U Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FO2 0.7 SHOW
279 6H11 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[(2~{R})-2-[(4-bromophenyl)carbonylamino]-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoyl]amino]azanium FHT 0.7 SHOW
280 6H4V Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(1-cyclopentylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQN 0.69 SHOW
281 5CEH Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 7-oxo-5-phenyl-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile 50P 0.69 SHOW
282 6H4O Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQH 0.68 SHOW
283 6F5Q Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-[2-(methylsulfonylamino)ethylamino]pyridine-4-carboxylic acid CTK 0.66 SHOW
284 5FP8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-[(4-methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acid AUY 0.66 SHOW
285 5FPB Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-(1H-pyrazol-4-yloxy)-3H-pyrido[3,4-d]pyrimidin-4-one HA6 0.65 SHOW
286 5FP7 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid YC8 0.65 SHOW
287 5FP4 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid YC8 0.65 SHOW
288 6H4W Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)-4-methyl-piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQQ 0.65 SHOW
289 6H4R Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQB 0.65 SHOW
290 6EJ1 Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 5-[1-[1-(2-chloranylethanoyl)piperidin-4-yl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile B7Q 0.64 SHOW
291 6BH4 Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 5-(1-tert-butyl-1H-pyrazol-4-yl)-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile DQS 0.63 SHOW
292 6EJ0 Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 7-oxidanylidene-6-propan-2-yl-5-[1-(1-prop-2-enoylpiperidin-4-yl)pyrazol-4-yl]-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile B7K 0.63 SHOW
293 6CG1 Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 3-{[(4-fluorophenyl)methyl]amino}pyridine-4-carboxylic acid QC1 0.62 SHOW
294 6H4T Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylethyl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FOW 0.62 SHOW
295 6DQF Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 2-{1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-yl}thieno[3,2-b]pyridine-7-carboxylic acid H61 0.62 SHOW
296 6H4S Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[3-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQE 0.62 SHOW
297 6H0X Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[(2~{R})-2-(5-phenylpentanoylamino)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoyl]amino]azanium FJB 0.6 SHOW
298 5LWB Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 5-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile 79H 0.6 SHOW
299 6DQC Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 2-[4-{[2-(dimethylamino)ethyl](ethyl)carbamoyl}-5-(4-methoxyphenyl)-1H-pyrazol-1-yl]pyridine-4-carboxylic acid H5Y 0.6 SHOW
300 6H4Z Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQ5 0.6 SHOW