97 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
51 2P94 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-((1R,2S) -2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)CYCLOHEXYL)-1H-INDOLE-6-CARBOXAMIDE ME4 0.86 SHOW
52 2FZZ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-(2'-{[(3R)-3-HYDROXYPYRROLIDIN-1-YL]METHYL}BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-1,4,5,6-TETRAHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE 5QC 0.86 SHOW
53 2XBX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3R,4R)-1-METHANESULFONYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} RR8 0.86 SHOW
54 2BQW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE IIE 0.86 SHOW
55 1FJS Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL)PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE Z34 0.86 SHOW
56 2Y80 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-{(3S)-1-[(1S)-1-(DIMETHYLAMINO)-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE 439 0.85 SHOW
57 3KQD Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'-(PYRROLIDIN-1-YLMETHYL)BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE LGL 0.85 SHOW
58 3CS7 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one LG0 0.85 SHOW
59 1FAX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid DX9 0.84 SHOW
60 1MQ5 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-[4-CHLORO-2-[[(4-CHLOROPHENYL)AMINO]CARBONYL]PHENYL]-4-[(4-METHYL-1-PIPERAZINYL)METHYL]-2-THIOPHENECARBOXAMIDE XLC 0.84 SHOW
61 2W26 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide RIV 0.84 SHOW
62 2Y7X Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-[(3S)-1-(5-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE MZA 0.84 SHOW
63 1G2M Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE R11 0.84 SHOW
64 2BOK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [AMINO (4-{(3AS,4R,8AS,8BR)-1,3-DIOXO-2- [3-(TRIMETHYLAMMONIO) PROPYL]DECAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL}PHENYL) METHYLENE]AMMONIUM 784 0.84 SHOW
65 1KSN Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) METHYL-3-(4'-N-OXOPYRIDYLPHENOYL)-3-METHYL-2-(M-AMIDINOBENZYL)-PROPIONATE FXV 0.84 SHOW
66 1LPZ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-carbamimidoylbenzyl)-N-(3,5-dichlorobenzyl)-4-methyl-1H-indole-2-carboxamide CMB 0.84 SHOW
67 1LPK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-CARBAMIMIDOYL-BENZYL)-1H-INDOLE-2-CARBOXYLIC ACID 3-CARBAMIMIDOYL-BENZYLESTER CBB 0.84 SHOW
68 2Y5F Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,2-OXAZOL-3-YL]-2-[3-[1-(2-HYDROXYETHYL)PYRROLIDIN-1-IUM-1-YL]PROPYL]-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZINE-1,3-DIONE XWG 0.84 SHOW
69 1LPG Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [4-({[5-BENZYLOXY-1-(3-CARBAMIMIDOYL-BENZYL)-1H-INDOLE-2-CARBONYL]-AMINO}-METHYL)-PHENYL]-TRIMETHYL-AMMONIUM IMA 0.84 SHOW
70 1J17 Anionic trypsin-2 Rattus norvegicus P00763 (TRY2_RAT) [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE ZEN 0.84 SHOW
71 2RA0 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(4-{2-[(dimethylamino)methyl]-1H-imidazol-1-yl}-2-fluorophenyl)-7-fluoro-1H-indazole-3-carboxamide JNJ 0.83 SHOW
72 3FFG Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (R)-6-(2'-((3-hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one FFG 0.83 SHOW
73 1IQH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XMF 0.83 SHOW
74 2XBW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3R,4R)-1-SULFAMOYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} 455 0.82 SHOW
75 1NFY Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE RTR 0.82 SHOW
76 4Y76 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N~2~-[(6-chloronaphthalen-2-yl)sulfonyl]-N~2~-{(3S)-1-[(2S)-1-(4-methyl-1,4-diazepan-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}glycinamide 4O1 0.82 SHOW
77 1XKA Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID 4PP 0.82 SHOW
78 1Y59 Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2,5-BIS-O-{3-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL1 0.82 SHOW
79 2BQ7 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(1-ISOPROPYLPIPERIDIN-4-YL)-1-(3-METHOXYBENZYL)-1H-INDOLE-2-CARBOXAMIDE IID 0.81 SHOW
80 3Q3K Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(2-{[(5-chloro-1H-indol-2-yl)carbonyl]amino}phenyl)-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide D90 0.81 SHOW
81 1IQJ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINECARBOXYLIC ACID ETHYL ESTER XMH 0.81 SHOW
82 1LQD Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-CARBAMIMIDOYL-BENZYL)-4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 3,5-DIMETHYL-BENZYLAMIDE CMI 0.8 SHOW
83 2D1J Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE D01 0.8 SHOW
84 3M37 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide M37 0.8 SHOW
85 1EZQ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER RPR 0.79 SHOW
86 1V2K Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE ZEN 0.79 SHOW
87 3UPE Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 1-[(7-carbamimidoylnaphthalen-2-yl)methyl]-6-({1-[(1Z)-ethanimidoyl]piperidin-4-yl}oxy)-2-(propan-2-yl)-1H-indole-4-carboxylic acid 0CA 0.78 SHOW
88 4O9V Suppressor of tumorigenicity 14 protein Homo sapiens Q9Y5Y6 (ST14_HUMAN) N-(trans-4-aminocyclohexyl)-3,5-bis(4-carbamimidoylphenoxy)benzamide NT4 0.75 SHOW
89 1Y5U Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2-O-{3-[AMINO(IMINO)METHYL]PHENYL}-5-O-{4-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL4 0.73 SHOW
90 4LXB Prothrombin Homo sapiens P00734 (THRB_HUMAN) 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide 7R9 0.71 SHOW
91 1F0S Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE PR2 0.71 SHOW
92 1Y5A Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2-O-{4-[AMINO(IMINO)METHYL]PHENYL}-5-O-{3-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL2 0.71 SHOW
93 4LOY Prothrombin Homo sapiens P00734 (THRB_HUMAN) 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-chloro-5-fluoro-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propyl]-amide 6XS 0.71 SHOW
94 6T7H Prothrombin Homo sapiens P00734 (THRB_HUMAN) macrocycle N14-PR4-A MRQ 0.7 SHOW
95 1W7G Prothrombin Homo sapiens P00734 (THRB_HUMAN) N-{(1S)-1-{[4-(3-AMINOPROPYL)PIPERAZIN-1-YL]CARBONYL}-4-[(DIAMINOMETHYLENE)AMINO]BUTYL}-3-(TRIFLUOROMETHYL)BENZENESULFONAMIDE MIU 0.66 SHOW
96 4YZU Coagulation factor IX Homo sapiens P00740 (FA9_HUMAN) N-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-4-(4H-1,2,4-triazol-4-yl)benzamide 4K6 0.62 SHOW
97 5TJX Plasma kallikrein Homo sapiens P03952 (KLKB1_HUMAN) (8E)-3-amino-1-methyl-15-[(1H-pyrazol-1-yl)methyl]-7,10,11,12,24,25-hexahydro-6H,18H,23H-19,22-(metheno)pyrido[4,3-j][1,9,13,17,18]benzodioxatriazacyclohenicosin-23-one GBT 0.6 SHOW