97 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 3IIT Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide D14 0.97 SHOW
2 1G2L Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER T87 0.91 SHOW
3 1LPZ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-carbamimidoylbenzyl)-N-(3,5-dichlorobenzyl)-4-methyl-1H-indole-2-carboxamide CMB 0.9 SHOW
4 1LPK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-CARBAMIMIDOYL-BENZYL)-1H-INDOLE-2-CARBOXYLIC ACID 3-CARBAMIMIDOYL-BENZYLESTER CBB 0.9 SHOW
5 1LPG Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [4-({[5-BENZYLOXY-1-(3-CARBAMIMIDOYL-BENZYL)-1H-INDOLE-2-CARBONYL]-AMINO}-METHYL)-PHENYL]-TRIMETHYL-AMMONIUM IMA 0.89 SHOW
6 2P93 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE ME1 0.88 SHOW
7 5K0H Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) O-benzyl-N-(benzylsulfonyl)-D-seryl-N-[(4-carbamimidoylphenyl)methyl]glycinamide 6PK 0.88 SHOW
8 1FJS Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL)PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE Z34 0.88 SHOW
9 3UPE Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 1-[(7-carbamimidoylnaphthalen-2-yl)methyl]-6-({1-[(1Z)-ethanimidoyl]piperidin-4-yl}oxy)-2-(propan-2-yl)-1H-indole-4-carboxylic acid 0CA 0.88 SHOW
10 1WU1 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE D91 0.87 SHOW
11 1Y59 Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2,5-BIS-O-{3-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL1 0.87 SHOW
12 1G2M Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE R11 0.87 SHOW
13 2Y7Z Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-[(3S)-1-[(1S)-1-DIMETHYLAMINO-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE C0Z 0.87 SHOW
14 2PHB Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE 230 0.87 SHOW
15 3TK6 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-[2-({[(5-chlorothiophen-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide D46 0.86 SHOW
16 1LQD Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-CARBAMIMIDOYL-BENZYL)-4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 3,5-DIMETHYL-BENZYLAMIDE CMI 0.86 SHOW
17 1NFW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE RRR 0.86 SHOW
18 1FAX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid DX9 0.86 SHOW
19 3KQC Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-(2'-(METHYLSULFONYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE LGK 0.85 SHOW
20 1KSN Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) METHYL-3-(4'-N-OXOPYRIDYLPHENOYL)-3-METHYL-2-(M-AMIDINOBENZYL)-PROPIONATE FXV 0.85 SHOW
21 1IQH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XMF 0.85 SHOW
22 2VVC Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-[(3S,4S)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-4-methoxypyrrolidin-3-yl]thiophene-2-carboxamide LZF 0.85 SHOW
23 3KQB Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE LGJ 0.85 SHOW
24 2RA0 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(4-{2-[(dimethylamino)methyl]-1H-imidazol-1-yl}-2-fluorophenyl)-7-fluoro-1H-indazole-3-carboxamide JNJ 0.85 SHOW
25 2D1J Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE D01 0.85 SHOW
26 3Q3K Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(2-{[(5-chloro-1H-indol-2-yl)carbonyl]amino}phenyl)-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide D90 0.85 SHOW
27 2VWO Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE LZG 0.85 SHOW
28 3FFG Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (R)-6-(2'-((3-hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one FFG 0.84 SHOW
29 2VVU Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide H22 0.84 SHOW
30 1J17 Anionic trypsin-2 Rattus norvegicus P00763 (TRY2_RAT) [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE ZEN 0.84 SHOW
31 2W26 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide RIV 0.84 SHOW
32 2BQ6 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-{[5-(5-CHLORO-2-THIENYL)ISOXAZOL-3-YL]METHYL}-3-CYANO-N-(1-ISOPROPYLPIPERIDIN-4-YL)-7-METHYL-1H-INDOLE-2-CARBOXAMIDE IIB 0.84 SHOW
33 1Z6E Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE IK8 0.84 SHOW
34 3KQD Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'-(PYRROLIDIN-1-YLMETHYL)BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE LGL 0.84 SHOW
35 2WYJ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE 898 0.83 SHOW
36 1EZQ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER RPR 0.83 SHOW
37 1IQG Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYIMINOMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XME 0.83 SHOW
38 3CS7 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one LG0 0.83 SHOW
39 2PR3 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE 237 0.83 SHOW
40 1V3X Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R)-4-[(6-CHLORO-2-NAPHTHYL)SULFONYL]-1-[(5-METHYL-4,5,6,7-TETRAHYDRO[1,3]THIAZOLO[5,4-C]PYRIDIN-2-YL)CARBONYL]PIPERAZINE-2-CARBOXAMIDE D76 0.83 SHOW
41 2P3T Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-4-(2-METHYLAMINO-IMIDAZOL-1-YLMETHYL)-THIOPHENE-2-CARBOXYLIC ACID [4-CHLORO-2-(5-CHLORO-PYRIDIN-2-YLCARBAMOYL)-6-METHOXY-PHENYL]-AMIDE 993 0.83 SHOW
42 2Q1J Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(butyl{[(4-chlorophenyl)amino]carbonyl}amino)-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]cyclopropanecarboxamide FXI 0.83 SHOW
43 1NFY Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE RTR 0.83 SHOW
44 2BQW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE IIE 0.83 SHOW
45 1IQK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XMI 0.83 SHOW
46 2Y5H Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3AS,4R,5S,8AS,8BR)-4-[2-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-4-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM Y5H 0.82 SHOW
47 2Y7X Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-[(3S)-1-(5-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE MZA 0.82 SHOW
48 2BQ7 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(1-ISOPROPYLPIPERIDIN-4-YL)-1-(3-METHOXYBENZYL)-1H-INDOLE-2-CARBOXAMIDE IID 0.82 SHOW
49 2Y5G Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-2-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM FJD 0.82 SHOW
50 2BOH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-{[5-(5-CHLORO-2-THIENYL)ISOXAZOL-3-YL]METHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE IIA 0.82 SHOW