98 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
51 2BQW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE IIE 0.85 SHOW
52 3CS7 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one LG0 0.85 SHOW
53 2VVC Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-[(3S,4S)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-4-methoxypyrrolidin-3-yl]thiophene-2-carboxamide LZF 0.85 SHOW
54 3Q3K Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(2-{[(5-chloro-1H-indol-2-yl)carbonyl]amino}phenyl)-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide D90 0.85 SHOW
55 3KQD Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'-(PYRROLIDIN-1-YLMETHYL)BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE LGL 0.84 SHOW
56 1G2L Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER T87 0.84 SHOW
57 1MQ6 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-[4-CHLORO-2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2-OXAZOLYL)METHYLAMINO]METHYL]-2-THIOPHENECARBOXAMIDE XLD 0.84 SHOW
58 1IQN Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[[4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-6-OXO-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINYL]CARBONYL]MORPHOLINE XMC 0.84 SHOW
59 1EZQ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER RPR 0.83 SHOW
60 3CEN Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE FXA 0.83 SHOW
61 2XBX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3R,4R)-1-METHANESULFONYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} RR8 0.83 SHOW
62 4ZHA Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(3S)-3-({[(E)-2-(5-chlorothiophen-2-yl)ethenyl]sulfonyl}amino)-2-oxo-2,3-dihydro-1H-pyrrol-1-yl]-3-fluoro-N-methylbenzamide 4O5 0.83 SHOW
63 2Y5F Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,2-OXAZOL-3-YL]-2-[3-[1-(2-HYDROXYETHYL)PYRROLIDIN-1-IUM-1-YL]PROPYL]-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZINE-1,3-DIONE XWG 0.82 SHOW
64 2BOK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [AMINO (4-{(3AS,4R,8AS,8BR)-1,3-DIOXO-2- [3-(TRIMETHYLAMMONIO) PROPYL]DECAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL}PHENYL) METHYLENE]AMMONIUM 784 0.82 SHOW
65 1G2M Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE R11 0.82 SHOW
66 2W3K Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R,4S)-N^1^-(4-chlorophenyl)-N^2^-[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]-4-hydroxy-4-phenylpyrrolidine-1,2-dicarboxamide L1D 0.82 SHOW
67 1V3X Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R)-4-[(6-CHLORO-2-NAPHTHYL)SULFONYL]-1-[(5-METHYL-4,5,6,7-TETRAHYDRO[1,3]THIAZOLO[5,4-C]PYRIDIN-2-YL)CARBONYL]PIPERAZINE-2-CARBOXAMIDE D76 0.82 SHOW
68 1IQK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XMI 0.81 SHOW
69 4O9V Suppressor of tumorigenicity 14 protein Homo sapiens Q9Y5Y6 (ST14_HUMAN) N-(trans-4-aminocyclohexyl)-3,5-bis(4-carbamimidoylphenoxy)benzamide NT4 0.81 SHOW
70 2WYJ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE 898 0.81 SHOW
71 2W26 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide RIV 0.8 SHOW
72 2D1J Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE D01 0.8 SHOW
73 3UPE Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 1-[(7-carbamimidoylnaphthalen-2-yl)methyl]-6-({1-[(1Z)-ethanimidoyl]piperidin-4-yl}oxy)-2-(propan-2-yl)-1H-indole-4-carboxylic acid 0CA 0.79 SHOW
74 1IQF Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R)-4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-6-OXO-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINECARBOXYLIC ACID ETHYL ESTER XMD 0.78 SHOW
75 2Y80 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-{(3S)-1-[(1S)-1-(DIMETHYLAMINO)-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE 439 0.78 SHOW
76 4Y76 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N~2~-[(6-chloronaphthalen-2-yl)sulfonyl]-N~2~-{(3S)-1-[(2S)-1-(4-methyl-1,4-diazepan-1-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}glycinamide 4O1 0.78 SHOW
77 2Y7X Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-[(3S)-1-(5-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE MZA 0.78 SHOW
78 1IQI Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL] METHYL]-2-PIPERAZINECARBOXYLIC ACID XMG 0.78 SHOW
79 2Y82 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE 930 0.78 SHOW
80 2P94 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-((1R,2S) -2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)CYCLOHEXYL)-1H-INDOLE-6-CARBOXAMIDE ME4 0.77 SHOW
81 1IQH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XMF 0.77 SHOW
82 1IOE Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (-)-7-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]TETRAHYDRO-8A-(METHOXYMETHYL)-1'-(4-PYRIDINYL)-SPIRO[5H-OXAZOLO[3,2-A]PYRAZINE-2(3H),4'-PIPERIDIN]-5-ONE XMA 0.76 SHOW
83 4Y6D Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(3S)-3-({[(E)-2-(5-chlorothiophen-2-yl)ethenyl]sulfonyl}amino)-2-oxopyrrolidin-1-yl]-3-fluoro-N,N-dimethylbenzamide 48U 0.76 SHOW
84 1Y5U Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2-O-{3-[AMINO(IMINO)METHYL]PHENYL}-5-O-{4-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL4 0.76 SHOW
85 1NFY Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE RTR 0.75 SHOW
86 3M37 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide M37 0.75 SHOW
87 1IQG Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYIMINOMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XME 0.74 SHOW
88 1V2K Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE ZEN 0.74 SHOW
89 1Y5A Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2-O-{4-[AMINO(IMINO)METHYL]PHENYL}-5-O-{3-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL2 0.74 SHOW
90 1IQJ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINECARBOXYLIC ACID ETHYL ESTER XMH 0.71 SHOW
91 6T7H Prothrombin Homo sapiens P00734 (THRB_HUMAN) macrocycle N14-PR4-A MRQ 0.69 SHOW
92 4LXB Prothrombin Homo sapiens P00734 (THRB_HUMAN) 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-difluoromethoxy-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-((S)-3-dimethylamino-pyrrolidin-1-yl)-3-oxo-propyl]-amide 7R9 0.68 SHOW
93 4LOY Prothrombin Homo sapiens P00734 (THRB_HUMAN) 5-Chloro-thiophene-2-carboxylic acid [(S)-2-[2-chloro-5-fluoro-3-(2-oxo-piperidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propyl]-amide 6XS 0.67 SHOW
94 1F0S Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE PR2 0.66 SHOW
95 1W7G Prothrombin Homo sapiens P00734 (THRB_HUMAN) N-{(1S)-1-{[4-(3-AMINOPROPYL)PIPERAZIN-1-YL]CARBONYL}-4-[(DIAMINOMETHYLENE)AMINO]BUTYL}-3-(TRIFLUOROMETHYL)BENZENESULFONAMIDE MIU 0.61 SHOW
96 4YZU Coagulation factor IX Homo sapiens P00740 (FA9_HUMAN) N-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-4-(4H-1,2,4-triazol-4-yl)benzamide 4K6 0.6 SHOW
97 5TJX Plasma kallikrein Homo sapiens P03952 (KLKB1_HUMAN) (8E)-3-amino-1-methyl-15-[(1H-pyrazol-1-yl)methyl]-7,10,11,12,24,25-hexahydro-6H,18H,23H-19,22-(metheno)pyrido[4,3-j][1,9,13,17,18]benzodioxatriazacyclohenicosin-23-one GBT 0.59 SHOW
98 4F8N pH 6 antigen Yersinia pestis P31522 (PSAA_YERPE) PHOSPHOCHOLINE PC 0.45 SHOW