306 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 5FYU Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) (3R)-3-azanyl-4-methyl-1,3-dihydroindol-2-one BY4 0.98 SHOW
2 6EJ1 Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 5-[1-[1-(2-chloranylethanoyl)piperidin-4-yl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile B7Q 0.84 SHOW
3 6EIU Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 8-oxidanyl-6-phenyl-7-propan-2-yl-imidazo[1,2-b]pyridazine-3-carbonitrile B6T 0.82 SHOW
4 6EJ0 Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 7-oxidanylidene-6-propan-2-yl-5-[1-(1-prop-2-enoylpiperidin-4-yl)pyrazol-4-yl]-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile B7K 0.81 SHOW
5 6DQ7 Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) N-{6-[4-(hydroxyacetyl)-1,4-diazepan-1-yl]-2-(pyridin-2-yl)pyrimidin-4-yl}-beta-alanine H6M 0.81 SHOW
6 6ETW Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [4-(2~{H}-1,2,3,4-tetrazol-5-yl)butanoylamino]azanium BX5 0.8 SHOW
7 6ETU Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[3-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]carbonylamino]azanium BWZ 0.79 SHOW
8 5IVE Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 5-methyl-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile 6E8 0.77 SHOW
9 6BH4 Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 5-(1-tert-butyl-1H-pyrazol-4-yl)-7-oxo-6-(propan-2-yl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile DQS 0.76 SHOW
10 6RBI Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 5-(1~{H}-1,2,3,4-tetrazol-5-yl)quinolin-8-ol JX8 0.76 SHOW
11 6DQE Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 2-(5-phenyl-4-{(R)-phenyl[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrazol-1-yl)pyridine-4-carboxylic acid H6A 0.72 SHOW
12 6ETV Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [3-(2~{H}-1,2,3,4-tetrazol-5-yl)propanoylamino]azanium BXE 0.7 SHOW
13 6H0W Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-phenyl-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHW 0.69 SHOW
14 6H0Y Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-(4-methoxyphenyl)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHZ 0.69 SHOW
15 6ETG Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[4-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]carbonylamino]azanium BWT 0.69 SHOW
16 6H11 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[(2~{R})-2-[(4-bromophenyl)carbonylamino]-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoyl]amino]azanium FHT 0.68 SHOW
17 6H0X Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[(2~{R})-2-(5-phenylpentanoylamino)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoyl]amino]azanium FJB 0.67 SHOW
18 5FP7 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid YC8 0.67 SHOW
19 5FP8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-[(4-methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acid AUY 0.66 SHOW
20 5FPB Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-(1H-pyrazol-4-yloxy)-3H-pyrido[3,4-d]pyrimidin-4-one HA6 0.66 SHOW
21 5F5C Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 8-[[(phenylmethyl)amino]methyl]-1~{H}-pyrido[3,4-d]pyrimidin-4-one 5V3 0.65 SHOW
22 6H4X Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(4-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FNQ 0.65 SHOW
23 6F5S Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-(3-morpholin-4-ylpropyl)-4-(2~{H}-1,2,3,4-tetrazol-5-yl)pyridine-2-carboxamide CQT 0.65 SHOW
24 6H4Y Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-(2-morpholin-4-ylethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FO8 0.65 SHOW
25 6H4R Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQB 0.65 SHOW
26 6H4P Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQ5 0.65 SHOW
27 5FPA Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3H-pyrido[3,4-d]pyrimidin-4-one N5J 0.65 SHOW
28 6H4T Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylethyl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FOW 0.65 SHOW
29 6DQF Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 2-{1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-yl}thieno[3,2-b]pyridine-7-carboxylic acid H61 0.65 SHOW
30 5PHI Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.65 SHOW
31 5PHA Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.65 SHOW
32 5PH7 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
33 5PK6 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
34 5PH1 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
35 5PHG Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
36 5PHM Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
37 5PNJ Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
38 5PHF Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
39 5PMC Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
40 5PH5 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
41 5PHK Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
42 5PH3 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
43 5PNA Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
44 5PIG Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
45 5PHN Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
46 5F5A Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-[(furan-2-ylmethylamino)methyl]pyridine-4-carboxylic acid 5V0 0.64 SHOW
47 5PHD Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
48 5PIK Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
49 5PHH Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW
50 5PMB Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.64 SHOW