304 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 6H0X Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[(2~{R})-2-(5-phenylpentanoylamino)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoyl]amino]azanium FJB 0.95 SHOW
2 6H11 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[(2~{R})-2-[(4-bromophenyl)carbonylamino]-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoyl]amino]azanium FHT 0.9 SHOW
3 5FP8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-[(4-methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acid AUY 0.89 SHOW
4 6CG1 Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 3-{[(4-fluorophenyl)methyl]amino}pyridine-4-carboxylic acid QC1 0.85 SHOW
5 5FPB Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-(1H-pyrazol-4-yloxy)-3H-pyrido[3,4-d]pyrimidin-4-one HA6 0.83 SHOW
6 6DQ7 Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) N-{6-[4-(hydroxyacetyl)-1,4-diazepan-1-yl]-2-(pyridin-2-yl)pyrimidin-4-yl}-beta-alanine H6M 0.78 SHOW
7 6F5Q Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-[2-(methylsulfonylamino)ethylamino]pyridine-4-carboxylic acid CTK 0.77 SHOW
8 6H0Y Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-(4-methoxyphenyl)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHZ 0.77 SHOW
9 6F5R Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-(3-oxidanylpropylamino)pyridine-4-carboxylic acid CQZ 0.77 SHOW
10 6DQE Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 2-(5-phenyl-4-{(R)-phenyl[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrazol-1-yl)pyridine-4-carboxylic acid H6A 0.76 SHOW
11 5PHC Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.75 SHOW
12 5PKP Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.75 SHOW
13 5PH8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.75 SHOW
14 5PJU Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.75 SHOW
15 5PH4 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.75 SHOW
16 5PIM Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.75 SHOW
17 5PL8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.75 SHOW
18 6DQF Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) 2-{1-[2-(piperidin-1-yl)ethyl]-1H-benzimidazol-2-yl}thieno[3,2-b]pyridine-7-carboxylic acid H61 0.74 SHOW
19 5F5A Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-[(furan-2-ylmethylamino)methyl]pyridine-4-carboxylic acid 5V0 0.73 SHOW
20 4D6Q Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) PYRIDINE-2,4-DICARBOXYLIC ACID PD2 0.73 SHOW
21 5F5C Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 8-[[(phenylmethyl)amino]methyl]-1~{H}-pyrido[3,4-d]pyrimidin-4-one 5V3 0.72 SHOW
22 6H0W Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-phenyl-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHW 0.72 SHOW
23 6H4R Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQB 0.72 SHOW
24 6H4Y Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-(2-morpholin-4-ylethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FO8 0.72 SHOW
25 6H4X Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(4-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FNQ 0.72 SHOW
26 6H4S Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[3-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQE 0.72 SHOW
27 6H4W Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)-4-methyl-piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQQ 0.71 SHOW
28 6H4P Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQ5 0.71 SHOW
29 6H4T Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylethyl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FOW 0.71 SHOW
30 6H4O Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQH 0.71 SHOW
31 6F5T Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-oxidanyl-4-(2~{H}-1,2,3,4-tetrazol-5-yl)pyridine-2-carboxamide CQK 0.71 SHOW
32 6H4V Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(1-cyclopentylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQN 0.7 SHOW
33 6H4U Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FO2 0.7 SHOW
34 6F5S Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-(3-morpholin-4-ylpropyl)-4-(2~{H}-1,2,3,4-tetrazol-5-yl)pyridine-2-carboxamide CQT 0.69 SHOW
35 5FPA Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3H-pyrido[3,4-d]pyrimidin-4-one N5J 0.68 SHOW
36 5PHD Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
37 5PNH Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
38 5PKL Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
39 4D6R Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
40 5PHL Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
41 5PLY Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
42 5PHA Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
43 5PMC Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
44 5PLD Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
45 5PIJ Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
46 5PLN Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
47 5PJ0 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
48 5PM1 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
49 5PMG Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW
50 5PLH Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.68 SHOW