97 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 4Y7B Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-chloro-N-{(3S)-1-[(2S)-1-{(1R,5S)-7-[2-(methylamino)ethyl]-3,7-diazabicyclo[3.3.1]non-3-yl}-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}naphthalene-2-sulfonamide 44I 0.98 SHOW
2 2Y7X Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-[(3S)-1-(5-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLIN-6-YL)-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE MZA 0.98 SHOW
3 3IIT Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide D14 0.98 SHOW
4 1V3X Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R)-4-[(6-CHLORO-2-NAPHTHYL)SULFONYL]-1-[(5-METHYL-4,5,6,7-TETRAHYDRO[1,3]THIAZOLO[5,4-C]PYRIDIN-2-YL)CARBONYL]PIPERAZINE-2-CARBOXAMIDE D76 0.98 SHOW
5 1NFX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-1-{[1-(2-HYDROXYETHYL)-1H-PYRROLO[3,2-C]PYRIDIN-2-YL]METHYL}PIPERAZIN-2-ONE RDR 0.97 SHOW
6 3CS7 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one LG0 0.97 SHOW
7 1MQ5 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-[4-CHLORO-2-[[(4-CHLOROPHENYL)AMINO]CARBONYL]PHENYL]-4-[(4-METHYL-1-PIPERAZINYL)METHYL]-2-THIOPHENECARBOXAMIDE XLC 0.97 SHOW
8 2BOH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-{[5-(5-CHLORO-2-THIENYL)ISOXAZOL-3-YL]METHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE IIA 0.96 SHOW
9 2BQW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE IIE 0.95 SHOW
10 2P93 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE ME1 0.95 SHOW
11 2Y80 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-{(3S)-1-[(1S)-1-(DIMETHYLAMINO)-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE 439 0.94 SHOW
12 1NFY Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE RTR 0.94 SHOW
13 2Y7Z Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-[(3S)-1-[(1S)-1-DIMETHYLAMINO-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE C0Z 0.94 SHOW
14 4Y6D Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(3S)-3-({[(E)-2-(5-chlorothiophen-2-yl)ethenyl]sulfonyl}amino)-2-oxopyrrolidin-1-yl]-3-fluoro-N,N-dimethylbenzamide 48U 0.93 SHOW
15 2Y82 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE 930 0.93 SHOW
16 1G2L Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER T87 0.92 SHOW
17 2VVC Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-[(3S,4S)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-4-methoxypyrrolidin-3-yl]thiophene-2-carboxamide LZF 0.92 SHOW
18 1V2K Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE ZEN 0.92 SHOW
19 1IOE Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (-)-7-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]TETRAHYDRO-8A-(METHOXYMETHYL)-1'-(4-PYRIDINYL)-SPIRO[5H-OXAZOLO[3,2-A]PYRAZINE-2(3H),4'-PIPERIDIN]-5-ONE XMA 0.92 SHOW
20 4A7I Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID [2-(1--ISOPROPYL-PIPERIDIN-4-YLSULFAMOYL)-ETHYL]-AMIDE A7I 0.92 SHOW
21 2D1J Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE D01 0.92 SHOW
22 2BQ7 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(1-ISOPROPYLPIPERIDIN-4-YL)-1-(3-METHOXYBENZYL)-1H-INDOLE-2-CARBOXAMIDE IID 0.92 SHOW
23 1IQH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XMF 0.92 SHOW
24 1IQI Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL] METHYL]-2-PIPERAZINECARBOXYLIC ACID XMG 0.91 SHOW
25 2W26 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide RIV 0.91 SHOW
26 2FZZ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-(2'-{[(3R)-3-HYDROXYPYRROLIDIN-1-YL]METHYL}BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-1,4,5,6-TETRAHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE 5QC 0.91 SHOW
27 1F0R Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE 815 0.91 SHOW
28 2W3K Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R,4S)-N^1^-(4-chlorophenyl)-N^2^-[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]-4-hydroxy-4-phenylpyrrolidine-1,2-dicarboxamide L1D 0.9 SHOW
29 2WYJ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE 898 0.89 SHOW
30 2Y5G Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-2-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM FJD 0.89 SHOW
31 2JKH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3~{a}~{S},4~{R},8~{a}~{S},8~{b}~{R})-4-[5-(5-chloranylthiophen-2-yl)-1,2-oxazol-3-yl]-1,3-bis(oxidanylidene)-4,6,7,8,8~{a},8~{b}-hexahydro-3~{a}~{H}-pyrrolo[3,4-a]pyrrolizin-2-yl]propyl-trimethyl-azanium BI7 0.89 SHOW
32 1NFW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE RRR 0.89 SHOW
33 2Y81 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2R)-2--PYRROLIDINYL] PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE 931 0.89 SHOW
34 2Y5H Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3AS,4R,5S,8AS,8BR)-4-[2-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-4-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM Y5H 0.88 SHOW
35 2P3U Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE 663 0.88 SHOW
36 2P95 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE ME5 0.87 SHOW
37 1MQ6 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-[4-CHLORO-2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2-OXAZOLYL)METHYLAMINO]METHYL]-2-THIOPHENECARBOXAMIDE XLD 0.87 SHOW
38 3KQB Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE LGJ 0.87 SHOW
39 1J17 Anionic trypsin-2 Rattus norvegicus P00763 (TRY2_RAT) [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE ZEN 0.87 SHOW
40 1EZQ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3'-AMINOMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-2-(3-CARBAMIMIDOYL-BENZYL)-BUTYRIC ACID METHYL ESTER RPR 0.87 SHOW
41 2PR3 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE 237 0.87 SHOW
42 2Y5F Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,2-OXAZOL-3-YL]-2-[3-[1-(2-HYDROXYETHYL)PYRROLIDIN-1-IUM-1-YL]PROPYL]-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZINE-1,3-DIONE XWG 0.87 SHOW
43 3KQD Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHENYL)-6-(2'-(PYRROLIDIN-1-YLMETHYL)BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-5,6-DIHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7(4H)-ONE LGL 0.86 SHOW
44 3Q3K Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(2-{[(5-chloro-1H-indol-2-yl)carbonyl]amino}phenyl)-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide D90 0.86 SHOW
45 2VVU Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide H22 0.86 SHOW
46 2XBY Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3R,4R)-1-METHYLCARBAMOYLMETHYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} 63C 0.86 SHOW
47 1WU1 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE D91 0.86 SHOW
48 2XBX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3R,4R)-1-METHANESULFONYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} RR8 0.85 SHOW
49 1Y59 Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2,5-BIS-O-{3-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL1 0.85 SHOW
50 3CEN Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE FXA 0.85 SHOW