304 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 6F5S Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) ~{N}-(3-morpholin-4-ylpropyl)-4-(2~{H}-1,2,3,4-tetrazol-5-yl)pyridine-2-carboxamide CQT 0.95 SHOW
2 5F5C Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 8-[[(phenylmethyl)amino]methyl]-1~{H}-pyrido[3,4-d]pyrimidin-4-one 5V3 0.93 SHOW
3 6H4P Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQ5 0.91 SHOW
4 6H4X Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(4-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FNQ 0.91 SHOW
5 6H4R Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQB 0.9 SHOW
6 6H4Y Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[4-(2-morpholin-4-ylethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FO8 0.9 SHOW
7 4D6Q Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) PYRIDINE-2,4-DICARBOXYLIC ACID PD2 0.9 SHOW
8 6H0X Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[(2~{R})-2-(5-phenylpentanoylamino)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoyl]amino]azanium FJB 0.9 SHOW
9 6H4T Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylethyl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FOW 0.9 SHOW
10 5FP7 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid YC8 0.89 SHOW
11 5FP8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 3-[(4-methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acid AUY 0.89 SHOW
12 5FPB Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-(1H-pyrazol-4-yloxy)-3H-pyrido[3,4-d]pyrimidin-4-one HA6 0.87 SHOW
13 6H4V Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(1-cyclopentylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQN 0.85 SHOW
14 6H4W Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-(3-chlorophenyl)-4-methyl-piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQQ 0.85 SHOW
15 6H4U Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FO2 0.84 SHOW
16 6ETV Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [3-(2~{H}-1,2,3,4-tetrazol-5-yl)propanoylamino]azanium BXE 0.84 SHOW
17 6H4S Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[3-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQE 0.84 SHOW
18 5F5A Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) 2-[(furan-2-ylmethylamino)methyl]pyridine-4-carboxylic acid 5V0 0.84 SHOW
19 6H0Y Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-(4-methoxyphenyl)-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHZ 0.83 SHOW
20 6H0W Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) (2~{R})-3-phenyl-2-(2~{H}-1,2,3,4-tetrazol-5-yl)propanehydrazide FHW 0.83 SHOW
21 6ETW Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [4-(2~{H}-1,2,3,4-tetrazol-5-yl)butanoylamino]azanium BX5 0.81 SHOW
22 6ETU Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[3-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]carbonylamino]azanium BWZ 0.8 SHOW
23 6ETG Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) [[4-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]carbonylamino]azanium BWT 0.79 SHOW
24 6DQ7 Lysine-specific demethylase 5A Homo sapiens P29375 (KDM5A_HUMAN) N-{6-[4-(hydroxyacetyl)-1,4-diazepan-1-yl]-2-(pyridin-2-yl)pyrimidin-4-yl}-beta-alanine H6M 0.79 SHOW
25 6H4O Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) 8-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one FQH 0.79 SHOW
26 2W2I Lysine-specific demethylase 4E Homo sapiens B2RXH2 (KDM4E_HUMAN) PYRIDINE-2,4-DICARBOXYLIC ACID PD2 0.78 SHOW
27 6EIU Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 8-oxidanyl-6-phenyl-7-propan-2-yl-imidazo[1,2-b]pyridazine-3-carbonitrile B6T 0.77 SHOW
28 6EJ1 Lysine-specific demethylase 5B Homo sapiens Q9UGL1 (KDM5B_HUMAN) 5-[1-[1-(2-chloranylethanoyl)piperidin-4-yl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile B7Q 0.77 SHOW
29 5PHI Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.77 SHOW
30 5PHF Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.77 SHOW
31 5PNV Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.77 SHOW
32 5PHK Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.77 SHOW
33 5PHG Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.77 SHOW
34 5PM9 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.77 SHOW
35 5PMR Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.77 SHOW
36 5PKS Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
37 5PM8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
38 5PLS Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
39 5PNA Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
40 5PM2 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
41 5PNR Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
42 5PLC Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
43 5PMB Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
44 5PN8 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
45 5PNP Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
46 5PHH Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
47 5PHM Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
48 5PHJ Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
49 5PHL Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW
50 5PL9 Lysine-specific demethylase 4D Homo sapiens Q6B0I6 (KDM4D_HUMAN) N-OXALYLGLYCINE OGA 0.76 SHOW