98 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 3IIT Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide D14 0.94 SHOW
2 1F0R Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE 815 0.92 SHOW
3 1NFX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-1-{[1-(2-HYDROXYETHYL)-1H-PYRROLO[3,2-C]PYRIDIN-2-YL]METHYL}PIPERAZIN-2-ONE RDR 0.92 SHOW
4 1NFW Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE RRR 0.92 SHOW
5 1Y59 Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2,5-BIS-O-{3-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL1 0.91 SHOW
6 1J17 Anionic trypsin-2 Rattus norvegicus P00763 (TRY2_RAT) [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE ZEN 0.89 SHOW
7 4Y7B Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-chloro-N-{(3S)-1-[(2S)-1-{(1R,5S)-7-[2-(methylamino)ethyl]-3,7-diazabicyclo[3.3.1]non-3-yl}-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl}naphthalene-2-sulfonamide 44I 0.89 SHOW
8 2W26 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide RIV 0.89 SHOW
9 2P93 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE ME1 0.88 SHOW
10 1XKA Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID 4PP 0.88 SHOW
11 2Y5H Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3AS,4R,5S,8AS,8BR)-4-[2-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-4-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM Y5H 0.88 SHOW
12 1WU1 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-2-({3-ISOBUTYL-4-[(5-PYRIDIN-4-YLPYRIMIDIN-2-YL)CARBONYL]PIPERAZIN-1-YL}SULFONYL)-1H-INDOLE D91 0.87 SHOW
13 1FJS Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-[2-[5-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY]-3,5-DIFLUORO-6-[3-(4,5-DIHYDRO-1-METHYL-1H-IMIDAZOL-2-YL)PHENOXY]PYRIDIN-4-YL]-N-METHYLGLYCINE Z34 0.87 SHOW
14 2PR3 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE 237 0.87 SHOW
15 2Y5G Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3AS,4R,5S,8AS,8BR)-4-[5-(5-CHLOROTHIOPHEN-2-YL)-1,3-OXAZOL-2-YL]-1,3-DIOXO-4,6,7,8,8A,8B-HEXAHYDRO-3AH-PYRROLO[3,4-A]PYRROLIZIN-2-YL]PROPYL-TRIMETHYL-AZANIUM FJD 0.87 SHOW
16 1LPZ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-carbamimidoylbenzyl)-N-(3,5-dichlorobenzyl)-4-methyl-1H-indole-2-carboxamide CMB 0.86 SHOW
17 2D1J Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE D01 0.86 SHOW
18 1G2L Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) [(1-{2[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-1-METHYL-1H-BENZOIMIDAZOL-5-YL}-CYCLOPROPYL)-PYRIDIN-2-YL-METHYLENEAMINOOXY]-ACETIC ACID ETHYL ESTER T87 0.86 SHOW
19 2Y82 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE 930 0.86 SHOW
20 2Y7Z Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-[(3S)-1-[(1S)-1-DIMETHYLAMINO-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE C0Z 0.85 SHOW
21 2VVU Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide H22 0.85 SHOW
22 2Y80 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-{(3S)-1-[(1S)-1-(DIMETHYLAMINO)-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE 439 0.85 SHOW
23 1Y5U Cationic trypsin Bos taurus P00760 (TRY1_BOVIN) 2-O-{3-[AMINO(IMINO)METHYL]PHENYL}-5-O-{4-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL TL4 0.85 SHOW
24 1KSN Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) METHYL-3-(4'-N-OXOPYRIDYLPHENOYL)-3-METHYL-2-(M-AMIDINOBENZYL)-PROPIONATE FXV 0.85 SHOW
25 1LQD Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-CARBAMIMIDOYL-BENZYL)-4-METHYL-1H-INDOLE-2-CARBOXYLIC ACID 3,5-DIMETHYL-BENZYLAMIDE CMI 0.85 SHOW
26 4A7I Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID [2-(1--ISOPROPYL-PIPERIDIN-4-YLSULFAMOYL)-ETHYL]-AMIDE A7I 0.85 SHOW
27 2WYJ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1-(DIMETHYLAMINO)ETHYL]-2-FLUOROPHENYL}-2-OXOPYRROLIDIN-3-YL]ETHENESULFONAMIDE 898 0.85 SHOW
28 3Q3K Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-(2-{[(5-chloro-1H-indol-2-yl)carbonyl]amino}phenyl)-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide D90 0.85 SHOW
29 2PHB Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE 230 0.85 SHOW
30 1IQG Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[4-HYDROXYIMINOMETHYL-1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XME 0.85 SHOW
31 4O9V Suppressor of tumorigenicity 14 protein Homo sapiens Q9Y5Y6 (ST14_HUMAN) N-(trans-4-aminocyclohexyl)-3,5-bis(4-carbamimidoylphenoxy)benzamide NT4 0.84 SHOW
32 1FAX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid DX9 0.84 SHOW
33 2JKH Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-[(3~{a}~{S},4~{R},8~{a}~{S},8~{b}~{R})-4-[5-(5-chloranylthiophen-2-yl)-1,2-oxazol-3-yl]-1,3-bis(oxidanylidene)-4,6,7,8,8~{a},8~{b}-hexahydro-3~{a}~{H}-pyrrolo[3,4-a]pyrrolizin-2-yl]propyl-trimethyl-azanium BI7 0.83 SHOW
34 2P3U Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE 663 0.83 SHOW
35 1G2M Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE R11 0.83 SHOW
36 2VWO Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE LZG 0.83 SHOW
37 3TK6 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) N-[2-({[(5-chlorothiophen-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide D46 0.83 SHOW
38 1Z6E Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-N-(4-{2-[(DIMETHYLAMINO)METHYL]-1H-IMIDAZOL-1-YL}-2-FLUOROPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE IK8 0.83 SHOW
39 1MQ6 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-[4-CHLORO-2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2-OXAZOLYL)METHYLAMINO]METHYL]-2-THIOPHENECARBOXAMIDE XLD 0.82 SHOW
40 2Y81 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2R)-2--PYRROLIDINYL] PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE 931 0.82 SHOW
41 1IQK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE XMI 0.82 SHOW
42 5K0H Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) O-benzyl-N-(benzylsulfonyl)-D-seryl-N-[(4-carbamimidoylphenyl)methyl]glycinamide 6PK 0.82 SHOW
43 1LPK Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(3-CARBAMIMIDOYL-BENZYL)-1H-INDOLE-2-CARBOXYLIC ACID 3-CARBAMIMIDOYL-BENZYLESTER CBB 0.82 SHOW
44 2XBX Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3R,4R)-1-METHANESULFONYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} RR8 0.82 SHOW
45 2P3T Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-4-(2-METHYLAMINO-IMIDAZOL-1-YLMETHYL)-THIOPHENE-2-CARBOXYLIC ACID [4-CHLORO-2-(5-CHLORO-PYRIDIN-2-YLCARBAMOYL)-6-METHOXY-PHENYL]-AMIDE 993 0.82 SHOW
46 1IQJ Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 4-[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]-2-PIPERAZINECARBOXYLIC ACID ETHYL ESTER XMH 0.81 SHOW
47 2XBY Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) (3R,4R)-1-METHYLCARBAMOYLMETHYL-PYRROLIDINE-3,4-DICARBOXYLIC ACID 3-[(4-CHLORO-PHENYL)-AMIDE] 4-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYL]-AMIDE} 63C 0.81 SHOW
48 2P95 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE ME5 0.81 SHOW
49 2Q1J Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 1-(butyl{[(4-chlorophenyl)amino]carbonyl}amino)-N-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]cyclopropanecarboxamide FXI 0.81 SHOW
50 2P94 Coagulation factor X Homo sapiens P00742 (FA10_HUMAN) 3-CHLORO-N-((1R,2S) -2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)CYCLOHEXYL)-1H-INDOLE-6-CARBOXAMIDE ME4 0.81 SHOW