40 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 6BPI Histone-lysine N-methyltransferase SETDB1 Homo sapiens Q15047 (SETB1_HUMAN) N-DIMETHYL-LYSINE MLY 0.72 SHOW
2 6BHE Histone-lysine N-methyltransferase SETDB1 Homo sapiens Q15047 (SETB1_HUMAN) N-TRIMETHYLLYSINE M3L 0.68 SHOW
3 5NRV DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 6-dipropylamino-1-hexanol 96K 0.6 SHOW
4 3QJ6 Hepatoma-derived growth factor-related protein 2 Homo sapiens Q7Z4V5 (HDGR2_HUMAN) N-TRIMETHYLLYSINE M3L 0.6 SHOW
5 5CIU DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) N-TRIMETHYLLYSINE M3L 0.59 SHOW
6 3QBY Hepatoma-derived growth factor-related protein 2 Homo sapiens Q7Z4V5 (HDGR2_HUMAN) N-TRIMETHYLLYSINE M3L 0.59 SHOW
7 6IIT Hepatoma-derived growth factor-related protein 3 Homo sapiens Q9Y3E1 (HDGR3_HUMAN) N-DIMETHYL-LYSINE MLY 0.56 SHOW
8 6KCU JIL-1 anchoring and stabilizing protein, isoform A Drosophila melanogaster Q9VAA9 (Q9VAA9_DROME) 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL BTB 0.54 SHOW
9 6IIS Hepatoma-derived growth factor-related protein 3 Homo sapiens Q9Y3E1 (HDGR3_HUMAN) N-TRIMETHYLLYSINE M3L 0.53 SHOW
10 5NRS DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) (2~{S})-1-[2-hydroxyethyl-[(2~{S})-2-oxidanylpropyl]amino]propan-2-ol 962 0.52 SHOW
11 5NRR DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 5-[2-hydroxyethyl(propyl)amino]pentan-1-ol 96E 0.52 SHOW
12 5NV0 DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 4-(dipropylamino)butanenitrile 9AH 0.52 SHOW
13 5VAR Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol 92Y 0.52 SHOW
14 6G2C Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)-1,2-oxazole EHT 0.51 SHOW
15 6G2E Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine EHH 0.51 SHOW
16 2LTO Tudor domain-containing protein 3 Homo sapiens Q9H7E2 (TDRD3_HUMAN) NG,NG-DIMETHYL-L-ARGININE DA2 0.5 SHOW
17 6G2O Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) [4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-phenyl]methanamine EJE 0.5 SHOW
18 6G25 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 3,5-dimethyl-4-(4-pyridin-4-yl-1~{H}-pyrazol-3-yl)-1,2-oxazole EHQ 0.49 SHOW
19 6G2F Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole EHW 0.49 SHOW
20 3QKJ DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL BTB 0.49 SHOW
21 2X4W Peregrin Homo sapiens P55201 (BRPF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.49 SHOW
22 6G29 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 5-methyl-2-piperidin-4-yl-6-pyridin-4-yl-pyridazin-3-one EHK 0.48 SHOW
23 4PL6 Protein MRG2 Arabidopsis thaliana Q4V3E2 (MRG2_ARATH) N-TRIMETHYLLYSINE M3L 0.48 SHOW
24 5D6Y Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) N-TRIMETHYLLYSINE M3L 0.47 SHOW
25 6G27 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 5-methyl-6-phenyl-2-piperidin-4-yl-pyridazin-3-one EHE 0.47 SHOW
26 6WAT PHD finger protein 1 Homo sapiens O43189 (PHF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.44 SHOW
27 6CK0 Biotin acetyl coenzyme A carboxylase synthetase Helicobacter pylori B5Z8D8 (B5Z8D8_HELPG) 5'-O-[(S)-({5-[(2R,3aS,4S,6aR)-2-hydroxyhexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}oxy){[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]adenosine F5D 0.44 SHOW
28 4N4H Zinc finger MYND domain-containing protein 11 Mus musculus Q8R5C8 (ZMY11_MOUSE) N-TRIMETHYLLYSINE M3L 0.44 SHOW
29 2GFA Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) N-TRIMETHYLLYSINE M3L 0.44 SHOW
30 4N4I Zinc finger MYND domain-containing protein 11 Mus musculus Q8R5C8 (ZMY11_MOUSE) N-TRIMETHYLLYSINE M3L 0.43 SHOW
31 6VN6 Ubiquitin carboxyl-terminal hydrolase 7 Homo sapiens Q93009 (UBP7_HUMAN) [(2R)-5-chloro-7-{2-[(2S)-1-chloro-2,3-dihydroxypropan-2-yl]thieno[3,2-b]pyridin-7-yl}-2,3-dihydro-1-benzofuran-2-yl](piperazin-1-yl)methanone R4J 0.42 SHOW
32 5YJ8 Tudor domain-containing protein 3 Homo sapiens Q9H7E2 (TDRD3_HUMAN) 5-(aminomethyl)-1,3-dimethyl-benzimidazol-2-one 8W9 0.42 SHOW
33 2Y56 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) [(1S,5R)-8-[(2R)-2-HYDROXY-2-PHENYL-ETHYL]-8-AZABICYCLO[3.2.1]OCTAN-3-YL] BENZOATE V11 0.41 SHOW
34 5VQH Tudor and KH domain-containing protein homolog Bombyx mori H9JD76 (TDRKH_BOMMO) N3, N4-DIMETHYLARGININE 2MR 0.41 SHOW
35 2X4X Peregrin Homo sapiens P55201 (BRPF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW
36 4HCZ PHD finger protein 1 Homo sapiens O43189 (PHF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW
37 6G2B Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 4-(3-methyl-5-phenyl-imidazol-4-yl)pyridine EH8 0.41 SHOW
38 6WAU PHD finger protein 19 Homo sapiens Q5T6S3 (PHF19_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW
39 4FL6 Lethal(3)malignant brain tumor-like protein 1 Homo sapiens Q96JM7 (LMBL3_HUMAN) [2-(phenylamino)benzene-1,4-diyl]bis{[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone} UWN 0.41 SHOW
40 6I8B Spindlin-1 Homo sapiens Q9Y657 (SPIN1_HUMAN) 2-[4-[2-[[2-[3-[2-azanyl-5-(cyclopropylmethoxy)-3,3-dimethyl-indol-6-yl]oxypropyl]-1,3-dihydroisoindol-5-yl]oxy]ethyl]-1,2,3-triazol-1-yl]-1-[4-(2-pyrrolidin-1-ylethyl)piperidin-1-yl]ethanone H7T 0.41 SHOW