35 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 6BHD Histone-lysine N-methyltransferase SETDB1 Homo sapiens Q15047 (SETB1_HUMAN) N-DIMETHYL-LYSINE MLY 0.68 SHOW
2 5NRV DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 6-dipropylamino-1-hexanol 96K 0.52 SHOW
3 5CIU DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) N-TRIMETHYLLYSINE M3L 0.5 SHOW
4 5NV2 DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) (2~{S})-6-methyl-~{N}-propan-2-yl-heptan-2-amine 9AE 0.49 SHOW
5 5NRS DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) (2~{S})-1-[2-hydroxyethyl-[(2~{S})-2-oxidanylpropyl]amino]propan-2-ol 962 0.48 SHOW
6 5NV0 DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 4-(dipropylamino)butanenitrile 9AH 0.48 SHOW
7 5NVO DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) CHOLINE ION CHT 0.48 SHOW
8 6G2B Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 4-(3-methyl-5-phenyl-imidazol-4-yl)pyridine EH8 0.48 SHOW
9 5D6Y Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) N-TRIMETHYLLYSINE M3L 0.47 SHOW
10 6G2C Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)-1,2-oxazole EHT 0.47 SHOW
11 5NR3 DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) Ethambutol 95E 0.47 SHOW
12 5VAR Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol 92Y 0.47 SHOW
13 3QJ6 Hepatoma-derived growth factor-related protein 2 Homo sapiens Q7Z4V5 (HDGR2_HUMAN) N-TRIMETHYLLYSINE M3L 0.46 SHOW
14 6IIT Hepatoma-derived growth factor-related protein 3 Homo sapiens Q9Y3E1 (HDGR3_HUMAN) N-DIMETHYL-LYSINE MLY 0.46 SHOW
15 6WAT PHD finger protein 1 Homo sapiens O43189 (PHF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.45 SHOW
16 5NRR DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 5-[2-hydroxyethyl(propyl)amino]pentan-1-ol 96E 0.45 SHOW
17 6G2F Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole EHW 0.45 SHOW
18 2LTO Tudor domain-containing protein 3 Homo sapiens Q9H7E2 (TDRD3_HUMAN) NG,NG-DIMETHYL-L-ARGININE DA2 0.45 SHOW
19 3QBY Hepatoma-derived growth factor-related protein 2 Homo sapiens Q7Z4V5 (HDGR2_HUMAN) N-TRIMETHYLLYSINE M3L 0.45 SHOW
20 6G25 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 3,5-dimethyl-4-(4-pyridin-4-yl-1~{H}-pyrazol-3-yl)-1,2-oxazole EHQ 0.44 SHOW
21 3QKJ DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL BTB 0.44 SHOW
22 6G2O Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) [4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-phenyl]methanamine EJE 0.44 SHOW
23 6IIS Hepatoma-derived growth factor-related protein 3 Homo sapiens Q9Y3E1 (HDGR3_HUMAN) N-TRIMETHYLLYSINE M3L 0.44 SHOW
24 4QQ6 Survival motor neuron protein Homo sapiens Q16637 (SMN_HUMAN) 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine 36X 0.43 SHOW
25 4PLI Protein MRG2 Arabidopsis thaliana Q4V3E2 (MRG2_ARATH) N-TRIMETHYLLYSINE M3L 0.43 SHOW
26 6KCU JIL-1 anchoring and stabilizing protein, isoform A Drosophila melanogaster Q9VAA9 (Q9VAA9_DROME) 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL BTB 0.43 SHOW
27 6BPI Histone-lysine N-methyltransferase SETDB1 Homo sapiens Q15047 (SETB1_HUMAN) N-DIMETHYL-LYSINE MLY 0.43 SHOW
28 4PL6 Protein MRG2 Arabidopsis thaliana Q4V3E2 (MRG2_ARATH) N-TRIMETHYLLYSINE M3L 0.42 SHOW
29 5XFR Metal-response element-binding transcription factor 2 Homo sapiens Q9Y483 (MTF2_HUMAN) N-TRIMETHYLLYSINE M3L 0.42 SHOW
30 6G27 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 5-methyl-6-phenyl-2-piperidin-4-yl-pyridazin-3-one EHE 0.42 SHOW
31 5VQH Tudor and KH domain-containing protein homolog Bombyx mori H9JD76 (TDRKH_BOMMO) N3, N4-DIMETHYLARGININE 2MR 0.42 SHOW
32 6G2E Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine EHH 0.42 SHOW
33 4IUU Protein SAWADEE HOMEODOMAIN HOMOLOG 1 Arabidopsis thaliana Q9XI47 (SHH1_ARATH) N-METHYL-LYSINE MLZ 0.42 SHOW
34 6WAV PHD finger protein 19 Homo sapiens Q5T6S3 (PHF19_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW
35 2GFA Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW