49 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 5D6Y Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) N-TRIMETHYLLYSINE M3L 0.89 SHOW
2 5VAR Lysine-specific demethylase 4A Homo sapiens O75164 (KDM4A_HUMAN) (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol 92Y 0.69 SHOW
3 2X4W Peregrin Homo sapiens P55201 (BRPF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.54 SHOW
4 2X4X Peregrin Homo sapiens P55201 (BRPF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.52 SHOW
5 3MO8 Peregrin Homo sapiens P55201 (BRPF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.51 SHOW
6 6IIT Hepatoma-derived growth factor-related protein 3 Homo sapiens Q9Y3E1 (HDGR3_HUMAN) N-DIMETHYL-LYSINE MLY 0.51 SHOW
7 6IIS Hepatoma-derived growth factor-related protein 3 Homo sapiens Q9Y3E1 (HDGR3_HUMAN) N-TRIMETHYLLYSINE M3L 0.5 SHOW
8 2LVM TP53-binding protein 1 Homo sapiens Q12888 (TP53B_HUMAN) N-DIMETHYL-LYSINE MLY 0.49 SHOW
9 2X4Y Peregrin Homo sapiens P55201 (BRPF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.48 SHOW
10 6G25 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 3,5-dimethyl-4-(4-pyridin-4-yl-1~{H}-pyrazol-3-yl)-1,2-oxazole EHQ 0.47 SHOW
11 6KCU JIL-1 anchoring and stabilizing protein, isoform A Drosophila melanogaster Q9VAA9 (Q9VAA9_DROME) 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL BTB 0.47 SHOW
12 2L12 Chromobox protein homolog 7 Homo sapiens O95931 (CBX7_HUMAN) N-TRIMETHYLLYSINE M3L 0.46 SHOW
13 6G2F Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-1,2-oxazole EHW 0.46 SHOW
14 3QBY Hepatoma-derived growth factor-related protein 2 Homo sapiens Q7Z4V5 (HDGR2_HUMAN) N-TRIMETHYLLYSINE M3L 0.46 SHOW
15 4BD3 PHD finger protein 19 Homo sapiens Q5T6S3 (PHF19_HUMAN) N-TRIMETHYLLYSINE M3L 0.45 SHOW
16 6WAU PHD finger protein 19 Homo sapiens Q5T6S3 (PHF19_HUMAN) N-TRIMETHYLLYSINE M3L 0.45 SHOW
17 4CRI TP53-binding protein 1 Homo sapiens Q12888 (TP53B_HUMAN) N-DIMETHYL-LYSINE MLY 0.44 SHOW
18 2VYT Sex comb on midleg-like protein 2 Homo sapiens Q9UQR0 (SCML2_HUMAN) N-METHYL-LYSINE MLZ 0.44 SHOW
19 6BHD Histone-lysine N-methyltransferase SETDB1 Homo sapiens Q15047 (SETB1_HUMAN) N-DIMETHYL-LYSINE MLY 0.44 SHOW
20 5XFQ PHD finger protein 1 Mus musculus Q9Z1B8 (PHF1_MOUSE) N-TRIMETHYLLYSINE M3L 0.44 SHOW
21 6G29 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 5-methyl-2-piperidin-4-yl-6-pyridin-4-yl-pyridazin-3-one EHK 0.44 SHOW
22 5CIU DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) N-TRIMETHYLLYSINE M3L 0.43 SHOW
23 3OMC Staphylococcal nuclease domain-containing protein 1 Homo sapiens Q7KZF4 (SND1_HUMAN) N3, N4-DIMETHYLARGININE 2MR 0.43 SHOW
24 6G27 Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 5-methyl-6-phenyl-2-piperidin-4-yl-pyridazin-3-one EHE 0.43 SHOW
25 6SZ8 YTH domain-containing protein 1 Homo sapiens Q96MU7 (YTDC1_HUMAN) 6-pyrrolidin-1-yl-5~{H}-pyrimidine-2,4-dione M1Z 0.43 SHOW
26 3OMG Staphylococcal nuclease domain-containing protein 1 Homo sapiens Q7KZF4 (SND1_HUMAN) N3, N4-DIMETHYLARGININE 2MR 0.43 SHOW
27 2RHI Lethal(3)malignant brain tumor-like protein 1 Homo sapiens Q9Y468 (LMBL1_HUMAN) N-DIMETHYL-LYSINE MLY 0.42 SHOW
28 6G2E Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) [3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)phenyl]methanamine EHH 0.42 SHOW
29 2RHX Lethal(3)malignant brain tumor-like protein 1 Homo sapiens Q9Y468 (LMBL1_HUMAN) N-DIMETHYL-LYSINE MLY 0.42 SHOW
30 3QJ6 Hepatoma-derived growth factor-related protein 2 Homo sapiens Q7Z4V5 (HDGR2_HUMAN) N-TRIMETHYLLYSINE M3L 0.42 SHOW
31 4FL6 Lethal(3)malignant brain tumor-like protein 1 Homo sapiens Q96JM7 (LMBL3_HUMAN) [2-(phenylamino)benzene-1,4-diyl]bis{[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone} UWN 0.42 SHOW
32 5NRV DNA (cytosine-5)-methyltransferase 3B Homo sapiens Q9UBC3 (DNM3B_HUMAN) 6-dipropylamino-1-hexanol 96K 0.42 SHOW
33 4HCZ PHD finger protein 1 Homo sapiens O43189 (PHF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.42 SHOW
34 6BPI Histone-lysine N-methyltransferase SETDB1 Homo sapiens Q15047 (SETB1_HUMAN) N-DIMETHYL-LYSINE MLY 0.42 SHOW
35 2RCW Poly [ADP-ribose] polymerase 1 Homo sapiens P09874 (PARP1_HUMAN) trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium AAI 0.42 SHOW
36 6G2C Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) 3,5-dimethyl-4-(1-methyl-5-pyridin-4-yl-imidazol-4-yl)-1,2-oxazole EHT 0.42 SHOW
37 2YKE Heat shock protein HSP 90-alpha Homo sapiens P07900 (HS90A_HUMAN) N-[(4R)-4-(3H-imidazo[4,5-c]pyridin-2-yl)-4H-fluoren-9-yl]quinoline-5-carboxamide YKE 0.42 SHOW
38 6YNN YTH domain-containing protein 1 Homo sapiens Q96MU7 (YTDC1_HUMAN) 6-[[(2-chloranyl-6-fluoranyl-phenyl)methyl-methyl-amino]methyl]-1~{H}-pyrimidine-2,4-dione P0B 0.42 SHOW
39 6WAV PHD finger protein 19 Homo sapiens Q5T6S3 (PHF19_HUMAN) N-TRIMETHYLLYSINE M3L 0.42 SHOW
40 6SZY YTH domain-containing protein 1 Homo sapiens Q96MU7 (YTDC1_HUMAN) 4-propan-2-yl-5,6,7,8-tetrahydro-4~{a}~{H}-quinazolin-2-one M5N 0.41 SHOW
41 4EDU Sex comb on midleg-like protein 2 Homo sapiens Q9UQR0 (SCML2_HUMAN) N-METHYL-LYSINE MLZ 0.41 SHOW
42 5M9N Tudor domain-containing protein 1 Homo sapiens Q9BXT4 (TDRD1_HUMAN) N3, N4-DIMETHYLARGININE 2MR 0.41 SHOW
43 4X34 TP53-binding protein 1 Homo sapiens Q12888 (TP53B_HUMAN) N-DIMETHYL-LYSINE MLY 0.41 SHOW
44 6WAT PHD finger protein 1 Homo sapiens O43189 (PHF1_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW
45 2RJE Lethal(3)malignant brain tumor-like protein 1 Homo sapiens Q9Y468 (LMBL1_HUMAN) N-DIMETHYL-LYSINE MLY 0.41 SHOW
46 6G2O Histone-lysine N-methyltransferase NSD3 Homo sapiens Q9BZ95 (NSD3_HUMAN) [4-[5-(7-fluoranylquinolin-4-yl)-1-methyl-imidazol-4-yl]-3,5-dimethyl-phenyl]methanamine EJE 0.41 SHOW
47 2IG0 TP53-binding protein 1 Homo sapiens Q12888 (TP53B_HUMAN) N-DIMETHYL-LYSINE MLY 0.41 SHOW
48 6BHE Histone-lysine N-methyltransferase SETDB1 Homo sapiens Q15047 (SETB1_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW
49 2K3Y Chromatin modification-related protein EAF3 Saccharomyces cerevisiae Q12432 (EAF3_YEAST) (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid M2L 0.41 SHOW