Protein

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Protein Name Polycomb protein EED
#PDB ID 34
Organism Homo sapiens
Uniprot ID/ACC O75530 (EED_HUMAN)
Protein Sequence MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
Protein Class TRANSCRIPTION REGULATOR
Synonym(s)
  •   polycomb protein EED
  • WD protein associating with integrin cytoplasmic tails 1
  • embryonic ectoderm development protein
  • COGIS
  • HEED
  • WAIT1
show 5 synonym(s)
Gene Symbol EED
Gene ID 8726
Pfam ID PF00400
Interpro ID IPR037352, IPR015943, IPR001680, IPR019775, IPR017986, IPR036322
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
LQF Small Molecule 5H19 IC50 : 320.0 nM Binding MOAD SHOW
73K Small Molecule 5GSA Kd : 82.5 nM Binding MOAD SHOW
73K Small Molecule 5WUK Kd : 14.0 nM Binding MOAD SHOW
LQA Small Molecule 5H13 IC50 : 11580.0 nM Binding MOAD SHOW
LQB Small Molecule 5H14 IC50 : 8760.0 nM Binding MOAD SHOW
7VY Small Molecule 5U5K IC50 : 95000.0 nM Binding MOAD SHOW
7W7 Small Molecule 5U5T IC50 : 3900.0 nM Binding MOAD SHOW
7XG Small Molecule 5U6D Ki : 2.6 nM Binding MOAD SHOW
82D Small Molecule 5U8A Ki : 13.0 nM Binding MOAD SHOW
82G Small Molecule 5U8F Ki : 11.0 nM Binding MOAD SHOW
LQD Small Molecule 5H15 IC50 : 1570.0 nM Binding MOAD SHOW
LQE Small Molecule 5H17 IC50 : 890.0 nM Binding MOAD SHOW
M3L H1K26me3 3IIY
-
-
SHOW
LQG Small Molecule 5H24
-
-
SHOW
M3L H3K27me3 5HYN
-
-
SHOW
M3L Peptidomimetic Ligands 5TTW
-
-
SHOW
M3L H4K20me3 3JPX
-
-
SHOW
Q3D Small Molecule 6W7F
-
-
SHOW
M3L H3K27me3 5LS6
-
-
SHOW
M3L H4K20me3 3IJ1
-
-
SHOW
LQH Small Molecule 5H25
-
-
SHOW
M3L H3K9me3 3K27
-
-
SHOW
6PU Small Molecule 5K0M
-
-
SHOW
L9K Small Molecule 6SFB
-
-
SHOW
NDS Small Molecule 3IJC
-
-
SHOW
M3L H3K27me3 3JZG
-
-
SHOW
Q3A Small Molecule 6W7G
-
-
SHOW
M3L JARID2 me3 6C23
-
-
SHOW
M3L H3K4me3 3K26
-
-
SHOW
M3L H3K79me3 3JZH
-
-
SHOW
M3L H3K27me3 6C24
-
-
SHOW
M3L H3K9me3 3IJ0
-
-
SHOW
M3L Jarid2-K116me3 4X3E
-
-
SHOW
M3L H3K27me3 3IIW
-
-
SHOW