Protein Download |
||||||
Protein Name | Lysine-specific demethylase 4A | |||||
---|---|---|---|---|---|---|
#PDB ID | 16 | |||||
Organism | Homo sapiens | |||||
Uniprot ID/ACC | O75164 (KDM4A_HUMAN) | |||||
Protein Sequence | MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDLSSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTGVLTVHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAEVADEYMFSLEENKKSKGRRQPLSKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME | |||||
Protein Class | TRANSCRIPTION REGULATOR | |||||
Synonym(s) |
|
|||||
Gene Symbol | KDM4A | |||||
Gene ID | 9682 | |||||
Pfam ID | PF02373, PF02375, PF18104 | |||||
Interpro ID | IPR034732, IPR003347, IPR003349, IPR040477, IPR002999, IPR011011, IPR001965, IPR013083 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
FQE | Small Molecule | 6H4S | Ki : 2.0 nM | Binding MOAD | SHOW | |
FQB | Small Molecule | 6H4R | Ki : 0.004 nM | Binding MOAD | SHOW | |
FOW | Small Molecule | 6H4T | Ki : 4.0 nM | Binding MOAD | SHOW | |
FQN | Small Molecule | 6H4V | IC50 : 613.0 nM | Binding MOAD | SHOW | |
FO8 | Small Molecule | 6H4Y | IC50 : 77.0 nM | Binding MOAD | SHOW | |
FNQ | Small Molecule | 6H4X | IC50 : 131.0 nM | Binding MOAD | SHOW | |
FQH | Small Molecule | 6H4O | IC50 : 128.0 nM | Binding MOAD | SHOW | |
FQ5 | Small Molecule | 6H4P | Ki : 3.0 nM | Binding MOAD | SHOW | |
92Y | Small Molecule | 5VAR | Kd : 81700.0 nM | Binding MOAD | SHOW | |
OGA | Small Molecule | 5LY2 |
- |
- |
SHOW | |
M3L | H3K23me3 | 5D6Y |
- |
- |
SHOW | |
M3L | H4K20me3 | 2QQS |
- |
- |
SHOW | |
FO2 | Small Molecule | 6H4U |
- |
- |
SHOW | |
QC1 | Small Molecule | 6CG1 |
- |
- |
SHOW | |
M3L | H3K4me3 | 2GFA |
- |
- |
SHOW | |
FQQ | Small Molecule | 6H4W |
- |
- |
SHOW |