80 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 6PV7 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens P32297 (ACHA3_HUMAN) (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE NCT 0.77 SHOW
2 3WTO Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine N2Y 0.76 SHOW
3 5KXI Neuronal acetylcholine receptor subunit alpha4beta-2 Homo sapiens P17787 (ACHB2_HUMAN) (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE NCT 0.73 SHOW
4 6QQO Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) 6-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]pyridine-3-carboxamide JC8 0.72 SHOW
5 6QKK Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) 4-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]benzamide H92 0.71 SHOW
6 6SGV Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) Hosieine LDQ 0.69 SHOW
7 4AFT Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) VARENICLINE QMR 0.68 SHOW
8 6USF Neuronal acetylcholine receptor subunit alpha-4 Homo sapiens P43681 (ACHA4_HUMAN) VARENICLINE QMR 0.67 SHOW
9 2YMD Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) SEROTONIN SRO 0.67 SHOW
10 6CNK Neuronal acetylcholine receptor subunit alpha4beta-2 Homo sapiens P17787 (ACHB2_HUMAN) (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE NCT 0.67 SHOW
11 5AIN Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) VARENICLINE QMR 0.67 SHOW
12 3WTN Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine N2Y 0.66 SHOW
13 3ZDH Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) (2R)-N,N-dimethyl-4-(1-methylimidazol-2-yl)oxy-butan-2-amine XRS 0.66 SHOW
14 6UR8 Neuronal acetylcholine receptor subunit alpha-4 Homo sapiens P43681 (ACHA4_HUMAN) VARENICLINE QMR 0.65 SHOW
15 5FJV Neuronal acetylcholine receptor subunit alpha-2 Homo sapiens Q15822 (ACHA2_HUMAN) EPIBATIDINE EPJ 0.65 SHOW
16 2BYQ Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) EPIBATIDINE EPJ 0.64 SHOW
17 1UV6 Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM CCE 0.64 SHOW
18 4FRR Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) 3-[(2S)-azetidin-2-ylmethoxy]-5-[(1S,2R)-2-(2-methoxyethyl)cyclopropyl]pyridine 0VC 0.64 SHOW
19 5KE4 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)-N,N-dimethylethanamine 6S7 0.63 SHOW
20 4UM3 Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 1-(6-bromopyridin-3-yl)-1,4-diazepane 09R 0.63 SHOW
21 6QQP Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) 2-[5-[(1~{R},2~{R},4~{S})-7-azabicyclo[2.2.1]heptan-2-yl]-2-fluoranyl-pyridin-3-yl]pyridine-4-carboxamide JCW 0.63 SHOW
22 5OA0 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) STRYCHNINE SY9 0.63 SHOW
23 5O87 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE NCT 0.62 SHOW
24 4AFG Achbp Capitella teleta I6L8L2 (I6L8L2_CAPTE) VARENICLINE QMR 0.62 SHOW
25 4ZK4 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) (5R)-1-methyl-7-[5-(propan-2-yloxy)pyridin-3-yl]-1,7-diazaspiro[4.4]nonane TII 0.62 SHOW
26 3SQ6 Neuronal acetylcholine receptor subunit alpha-7, Acetylcholine-binding protein Homo sapiens / Lymnaea stagnalis - EPIBATIDINE EPJ 0.62 SHOW
27 2XZ5 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) ACETYLCHOLINE ACH 0.62 SHOW
28 3ZDG Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 3-(dimethylamino)butyl dimethylcarbamate XRX 0.61 SHOW
29 4ZRU Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 3-[(2S)-pyrrolidin-2-ylethynyl]pyridine TI9 0.61 SHOW
30 5OUH Acetylcholine binding protein Homo sapiens - Alpha-Lobeline L0B 0.6 SHOW
31 4UM1 Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 1-(5-ethoxypyridin-3-yl)-1,4-diazepane 09P 0.6 SHOW
32 6CNJ Neuronal acetylcholine receptor subunit alpha4beta-2 Homo sapiens P17787 (ACHB2_HUMAN) (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE NCT 0.59 SHOW
33 2ZJV Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine CT4 0.58 SHOW
34 5OUG Acetylcholine binding protein Homo sapiens - Alpha-Lobeline L0B 0.58 SHOW
35 5BP0 Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 5-fluoronicotine FN1 0.58 SHOW
36 3WIP Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) ACETYLCHOLINE ACH 0.58 SHOW
37 4BQT Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) (1R,5S)-1,2,3,4,5,6-HEXAHYDRO-8H-1,5-METHANOPYRIDO[1,2-A][1,5]DIAZOCIN-8-ONE C5E 0.58 SHOW
38 5BRX Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) (2R,3S,5R,7S)-2-(pyridin-3-yl)-1-azatricyclo[3.3.1.1~3,7~]decane TI4 0.57 SHOW
39 5SYO Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) (1R,5S)-1,2,3,4,5,6-HEXAHYDRO-8H-1,5-METHANOPYRIDO[1,2-A][1,5]DIAZOCIN-8-ONE C5E 0.57 SHOW
40 3U8L Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 1-(5-phenylpyridin-3-yl)-1,4-diazepane 09Q 0.56 SHOW
41 4ALX Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) (4bS,6S)-6-methoxy-1,4,6,7,9,10,12,13-octahydro-3H,5H-pyrano[4',3':3,4]pyrido[2,1-i]indol-3-one IZN 0.56 SHOW
42 1UW6 Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE NCT 0.56 SHOW
43 4B5D Achbp Capitella teleta I6L8L2 (I6L8L2_CAPTE) 2-[(1R,2S)-2-[5-[[(2S)-azetidin-2-yl]methoxy]pyridin-3-yl]cyclopropyl]ethanol SW4 0.56 SHOW
44 2ZJU Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine IM4 0.55 SHOW
45 5Y2Q Acetylcholine-binding protein Lymnaea stagnalis P58154 (ACHP_LYMST) 3-[[4-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]methoxy]pyridine 8L3 0.54 SHOW
46 5BW2 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) (2R)-2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane 4VU 0.54 SHOW
47 4AFH Achbp Capitella teleta I6L8L2 (I6L8L2_CAPTE) Alpha-Lobeline L0B 0.54 SHOW
48 6SH0 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) 1-[(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl]ethanone 4P0 0.53 SHOW
49 2Y56 Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) [(1S,5R)-8-[(2R)-2-HYDROXY-2-PHENYL-ETHYL]-8-AZABICYCLO[3.2.1]OCTAN-3-YL] BENZOATE V11 0.53 SHOW
50 4DBM Soluble acetylcholine receptor Aplysia californica Q8WSF8 (Q8WSF8_APLCA) (3-exo)-8,8-dimethyl-3-(4-{[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]methyl}-1H-1,2,3-triazol-1-yl)-8-azoniabicyclo[3.2.1]octane 0J0 0.53 SHOW