37 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 5U5T Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) (3R)-3-[(2H-1,3-benzodioxol-4-yl)methyl]piperidine-1-carboximidamide 7W7 0.97 SHOW
2 5U8A Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) (3R,4S)-1-[(2-bromo-6-fluorophenyl)methyl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine 82D 0.96 SHOW
3 5U8F Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) (3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-(1-methyl-1H-indol-3-yl)pyrrolidin-3-amine 82G 0.96 SHOW
4 5H14 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 2-[3-(3,5-dimethylpyrazol-1-yl)-4-nitro-phenyl]-3,4-dihydro-1H-isoquinoline LQB 0.92 SHOW
5 5H17 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) (3R,4aS,10aS)-6-methoxy-3-[(3-methoxyphenyl)methyl]-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline LQE 0.9 SHOW
6 5U5K Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) (3R)-3-[(3-methoxyphenyl)methyl]piperidine 7VY 0.88 SHOW
7 5U6D Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 2-[4-(4-{(3S,4R)-4-(dimethylamino)-1-[(2-fluoro-6-methylphenyl)methyl]pyrrolidin-3-yl}phenyl)-1H-pyrazol-1-yl]acetamide 7XG 0.85 SHOW
8 5K0M Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) (3R,4S)-1-[(1S)-7-fluoro-2,3-dihydro-1H-inden-1-yl]-N,N-dimethyl-4-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}pyrrolidin-3-amine 6PU 0.84 SHOW
9 6W7G Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 8-(2,6-dimethylpyridin-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-1-(methylsulfonyl)imidazo[1,5-c]pyrimidin-5-amine Q3A 0.8 SHOW
10 5H13 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 4-azanylidene-2-(3-methoxy-4-propan-2-yloxy-phenyl)-6,7-dihydro-[1,3]benzodioxolo[6,5-a]quinolizine-3-carbonitrile LQA 0.76 SHOW
11 6SFB Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) (~{E})-~{N}-(1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-6~{H}-[1,2,4]triazolo[4,3-c]pyrimidin-5-imine L9K 0.74 SHOW
12 5H25 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 5-(2-fluorophenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline LQH 0.73 SHOW
13 5H24 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 5-(furan-2-ylmethylamino)-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrile LQG 0.73 SHOW
14 5WUK Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 73K 0.7 SHOW
15 3IJC Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) ETHYL DIMETHYL AMMONIO PROPANE SULFONATE NDS 0.7 SHOW
16 5GSA Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-(furan-2-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 73K 0.69 SHOW
17 5H19 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile LQF 0.69 SHOW
18 6W7F Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) 8-(6-cyclopropylpyridin-3-yl)-N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-1-(methylsulfonyl)imidazo[1,5-c]pyrimidin-5-amine Q3D 0.69 SHOW
19 5WFC WD_REPEATS_REGION domain-containing protein Chaetomium thermophilum G0S8H7 (G0S8H7_CHATD) N-TRIMETHYLLYSINE M3L 0.58 SHOW
20 5KKL WD_REPEATS_REGION domain-containing protein Chaetomium thermophilum G0S8H7 (G0S8H7_CHATD) N-TRIMETHYLLYSINE M3L 0.57 SHOW
21 3K26 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.57 SHOW
22 3JZG Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.54 SHOW
23 5M5G WD_REPEATS_REGION domain-containing protein Chaetomium thermophilum G0S8H7 (G0S8H7_CHATD) N-TRIMETHYLLYSINE M3L 0.54 SHOW
24 6C24 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.54 SHOW
25 5KJH WD_REPEATS_REGION domain-containing protein Chaetomium thermophilum G0S8H7 (G0S8H7_CHATD) N-TRIMETHYLLYSINE M3L 0.53 SHOW
26 3K27 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.53 SHOW
27 3IIW Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.53 SHOW
28 3JPX Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.53 SHOW
29 5HYN Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.53 SHOW
30 3IJ1 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.52 SHOW
31 5LS6 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.52 SHOW
32 5TTW Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.51 SHOW
33 3JZH Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.45 SHOW
34 3IIY Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.45 SHOW
35 3IJ0 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.45 SHOW
36 4X3E Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.44 SHOW
37 6C23 Polycomb protein EED Homo sapiens O75530 (EED_HUMAN) N-TRIMETHYLLYSINE M3L 0.41 SHOW