Protein Download |
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Protein Name | Lysine-specific demethylase 5B | |||||
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#PDB ID | 10 | |||||
Organism | Homo sapiens | |||||
Uniprot ID/ACC | Q9UGL1 (KDM5B_HUMAN) | |||||
Protein Sequence | MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK | |||||
Protein Class | TRANSCRIPTION REGULATOR | |||||
Synonym(s) |
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Gene Symbol | KDM5B | |||||
Gene ID | 10765 | |||||
Pfam ID | PF01388, PF02373, PF02375, PF00628, PF08429, PF02928 | |||||
Interpro ID | IPR001606, IPR036431, IPR003347, IPR003349, IPR013637, IPR019786, IPR004198, IPR011011, IPR001965, IPR019787, IPR013083 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
FQ5 | Small Molecule | 6H4Z | Ki : 2.0 nM | Binding MOAD | SHOW | |
FQN | Small Molecule | 6H52 | IC50 : 68.0 nM | Binding MOAD | SHOW | |
0TI | Small Molecule | 5FZH |
- |
- |
SHOW | |
B7Q | Small Molecule | 6EJ1 |
- |
- |
SHOW | |
B6W | Small Molecule | 6EIY |
- |
- |
SHOW | |
B6T | Small Molecule | 6EIU |
- |
- |
SHOW | |
79H | Small Molecule | 5LWB |
- |
- |
SHOW | |
BY4 | Small Molecule | 5FYU |
- |
- |
SHOW | |
B7K | Small Molecule | 6EJ0 |
- |
- |
SHOW | |
JX8 | Small Molecule | 6RBI |
- |
- |
SHOW |