40 complex(es)
PDB ID
Protein Name
Organism
Uniprot ID/ACC
Ligand Name
HET ID
Structure
PS-Score (Pocket Similarity)
Card
1 3AM7 Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.93 SHOW
2 4AZA Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE MGO 0.92 SHOW
3 5J5O Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) 5'-O-[(R)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]-7-methylguanosine 6G0 0.91 SHOW
4 4TPW Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.88 SHOW
5 1L8B Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.87 SHOW
6 2V8Y Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) P-FLUORO-7-BENZYL GUANINE MONOPHOSPHATE MGV 0.87 SHOW
7 5T46 Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.86 SHOW
8 2V8X Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 7-BENZYL GUANINE MONOPHOSPHATE MGQ 0.85 SHOW
9 6GKK Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(sulfanyl)phosphoryl] hydrogen phosphate WZO 0.85 SHOW
10 5T48 Eukaryotic translation initiation factor 4E1 Drosophila melanogaster P48598 (IF4E_DROME) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.85 SHOW
11 1IPC Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.85 SHOW
12 5M7X Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(selanyl)phosphoryl] hydrogen phosphate RSE 0.84 SHOW
13 6GKJ Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.84 SHOW
14 5M7V Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(sulfanyl)phosphoryl] hydrogen phosphate WZO 0.84 SHOW
15 2W97 Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE MGO 0.84 SHOW
16 5M83 Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl hydrogen phosphate YDZ 0.84 SHOW
17 1IPB Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE GTA 0.84 SHOW
18 5ZK7 Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE MGT 0.84 SHOW
19 5J5Y Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 2-amino-9-{5-O-[(R)-{[(S)-{dichloro[(R)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2-O-methyl-beta-D-ribofuranosyl}-7-methyl-9H-purin-7-ium-6-olate 6G6 0.84 SHOW
20 4TQC Eukaryotic translation initiation factor 4E Homo sapiens P06730 (IF4E_HUMAN) 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE M7G 0.83 SHOW
21 5OSX Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [(2~{S},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl-[[[(3~{R},4~{S})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-phosphinic acid AKW 0.83 SHOW
22 4TQB Eukaryotic translation initiation factor 4E1 Drosophila melanogaster P48598 (IF4E_DROME) 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE MGT 0.82 SHOW
23 1EJH Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE M7G 0.82 SHOW
24 5ABU Eukaryotic translation initiation factor 4E-binding protein Mextli Drosophila melanogaster Q9VR35 (MXT_DROME) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE GTG 0.81 SHOW
25 1EJ1 Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE M7G 0.81 SHOW
26 3M94 Eukaryotic translation initiation factor 4E-binding protein 1 Homo sapiens Q13541 (4EBP1_HUMAN) N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate) M7M 0.78 SHOW
27 5ABX Eukaryotic translation initiation factor 4E-3 Caenorhabditis elegans O61955 (IF4E3_CAEEL) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.78 SHOW
28 6YLV Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) 4-Cl-Bn7GpppG mRNA 5' cap analog OYW 0.78 SHOW
29 6GKL Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-azanyl-4,5-dihydropurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate G0Z 0.77 SHOW
30 5BXV Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.76 SHOW
31 5M84 Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl hydrogen phosphate YDZ 0.76 SHOW
32 5M7Z Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [[[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-selanyl-phosphoryl] [(2~{R},3~{S},4~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 7LO 0.76 SHOW
33 2IDV Eukaryotic translation initiation factor 4E-1 Triticum aestivum P29557 (IF4E1_WHEAT) 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE M7G 0.75 SHOW
34 5M7W Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(sulfanyl)phosphoryl] hydrogen phosphate WZO 0.75 SHOW
35 6FC1 Eukaryotic translation initiation factor 4E Saccharomyces cerevisiae P07260 (IF4E_YEAST) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.74 SHOW
36 3HXI Eukaryotic Translation Initiation 4E Schistosoma mansoni - 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE GTG 0.72 SHOW
37 6YLR Eukaryotic translation initiation factor 4E Mus musculus P63073 (IF4E_MOUSE) bn7GpppG mRNA 5' cap analog OYE 0.67 SHOW
38 1WKW Eukaryotic translation initiation factor 4E-binding protein 1 Homo sapiens Q13541 (4EBP1_HUMAN) P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE GTA 0.6 SHOW
39 2JGB Eukaryotic translation initiation factor 4E type 2 Homo sapiens O60573 (IF4E2_HUMAN) 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE MGT 0.58 SHOW
40 6O80 Putative Eukaryotic translation initiation factor 4E type 5 Trypanosoma cruzi A0A2V2VRR6 (A0A2V2VRR6_TRYCR) 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE MGP 0.43 SHOW