14 Residue(s) |
Residue Name | #Ligands | #Proteins |
#Warheads | #Mechamisms |
#Protein-Ligand Complex(es) |
1 | ARG | 1 | 2 | 1 | 1 | 2 |
2 | ASN | 1 | 1 | 1 | 1 | 1 |
3 | ASP | 39 | 30 | 7 | 4 | 59 |
4 | CYS | 748 | 291 | 59 | 16 | 959 |
5 | GLU | 56 | 52 | 13 | 9 | 96 |
6 | GLY | 2 | 2 | 1 | 1 | 2 |
7 | HIS | 42 | 35 | 14 | 10 | 63 |
8 | LYS | 126 | 89 | 24 | 13 | 205 |
9 | MET | 3 | 3 | 4 | 3 | 3 |
10 | PRO | 9 | 3 | 5 | 5 | 9 |
11 | SER | 462 | 222 | 38 | 14 | 830 |
12 | THR | 33 | 20 | 12 | 8 | 47 |
13 | TYR | 19 | 18 | 9 | 7 | 32 |
14 | VAL | 8 | 1 | 2 | 2 | 10 |
Peculiar cases: For all identified residues, only Gly and Val were identified to form covalent bonds via their N-termini, in each case with the same protein. Gly and Val form covalent bonds with ubiquitin and haemoglobin, respectively.