10 mechanism(s) |
Mechanism Name | #Ligands | #Proteins |
#Warheads | #Residues |
#Protein-Ligand Complex(es) |
| 1 | Borylation | 132 | 56 | 3 | 4 | 200 |
| 2 | Composite Reaction | 31 | 30 | 14 | 8 | 42 |
| 3 | Epoxide Opening | 69 | 53 | 1 | 7 | 116 |
| 4 | Hemiaminalization | 10 | 10 | 2 | 2 | 13 |
| 5 | Hemi(thio)acetalization | 180 | 82 | 4 | 5 | 243 |
| 6 | Lactone Addition | 23 | 17 | 4 | 4 | 29 |
| 7 | Michael Addition | 289 | 116 | 11 | 5 | 363 |
| 8 | Nucleophilic Aliphatic Subsititution | 167 | 112 | 18 | 10 | 226 |
| 9 | Nucleophilic Aromatic Substitution | 29 | 25 | 7 | 5 | 43 |
| 10 | Phosphorylation | 63 | 65 | 6 | 6 | 116 |