9 mechanism(s) |
Mechanism Name | #Ligands | #Proteins |
#Warheads | #Residues |
#Protein-Ligand Complex(es) |
| 1 | Aziridine Opening | 15 | 14 | 1 | 3 | 18 |
| 2 | Borylation | 132 | 56 | 3 | 4 | 200 |
| 3 | Composite Reaction | 31 | 30 | 14 | 8 | 42 |
| 4 | Epoxide Opening | 69 | 53 | 1 | 7 | 116 |
| 5 | Lactone Addition | 23 | 17 | 4 | 4 | 29 |
| 6 | Nucleophilic Acyl Substitution | 92 | 96 | 17 | 8 | 140 |
| 7 | Nucleophilic Addition to a Double Bond | 30 | 25 | 13 | 4 | 44 |
| 8 | Nucleophilic Aliphatic Subsititution | 167 | 112 | 18 | 10 | 226 |
| 9 | Ring Opening | 32 | 24 | 13 | 6 | 41 |