7 mechanism(s) |
Mechanism Name | #Ligands | #Proteins |
#Warheads | #Residues |
#Protein-Ligand Complex(es) |
| 1 | Composite Reaction | 31 | 30 | 14 | 8 | 42 |
| 2 | Hemi(thio)acetalization | 180 | 82 | 4 | 5 | 243 |
| 3 | Nucleophilic Acyl Substitution | 92 | 96 | 17 | 8 | 140 |
| 4 | Nucleophilic Addition to a Triple Bond | 94 | 26 | 4 | 4 | 100 |
| 5 | Nucleophilic Aliphatic Subsititution | 167 | 112 | 18 | 10 | 226 |
| 6 | Phosphorylation | 63 | 65 | 6 | 6 | 116 |
| 7 | Sulfonylation | 21 | 21 | 2 | 3 | 30 |