5 mechanism(s) |
Mechanism Name | #Ligands | #Proteins |
#Warheads | #Residues |
#Protein-Ligand Complex(es) |
| 1 | Michael Addition | 289 | 116 | 11 | 5 | 363 |
| 2 | Nucleophilic Addition to a Double Bond | 30 | 25 | 13 | 4 | 44 |
| 3 | Nucleophilic Aliphatic Subsititution | 167 | 112 | 18 | 10 | 226 |
| 4 | Nucleophilic Aromatic Substitution | 29 | 25 | 7 | 5 | 43 |
| 5 | Ring Opening | 32 | 24 | 13 | 6 | 41 |