14 mechanism(s)
Mechanism Name
#Ligands
#Proteins
#Warheads
#Residues
#Protein-Ligand Complex(es)
1 Beta-Lactam Addition 101 78 1 3 280
2 Borylation 132 56 3 4 200
3 Composite Reaction 31 30 14 8 42
4 Hemi(thio)acetalization 180 82 4 5 243
5 Imidazolidinone Opening 11 25 1 1 53
6 Lactone Addition 23 17 4 4 29
7 Nucleophilic Acyl Substitution 92 96 17 8 140
8 Nucleophilic Addition to a Double Bond 30 25 13 4 44
9 Nucleophilic Addition to a Triple Bond 94 26 4 4 100
10 Nucleophilic Aliphatic Subsititution 167 112 18 10 226
11 Nucleophilic Aromatic Substitution 29 25 7 5 43
12 Phosphorylation 63 65 6 6 116
13 Ring Opening 32 24 13 6 41
14 Sulfonylation 21 21 2 3 30