| 1 | Aziridine Opening |
15 |
14 |
1 |
3 |
18 |
| 2 | Beta-Lactam Addition |
101 |
78 |
1 |
3 |
280 |
| 3 | Composite Reaction |
31 |
30 |
14 |
8 |
42 |
| 4 | Cyclohemiaminoacetalization |
11 |
7 |
4 |
2 |
12 |
| 5 | Disulfide Formation |
51 |
35 |
3 |
1 |
62 |
| 6 | Epoxide Opening |
69 |
53 |
1 |
7 |
116 |
| 7 | Hemi(thio)acetalization |
180 |
82 |
4 |
5 |
243 |
| 8 | Lactone Addition |
23 |
17 |
4 |
4 |
29 |
| 9 | Michael Addition |
289 |
116 |
11 |
5 |
363 |
| 10 | Nucleophilic Acyl Substitution |
92 |
96 |
17 |
8 |
140 |
| 11 | Nucleophilic Addition to a Double Bond |
30 |
25 |
13 |
4 |
44 |
| 12 | Nucleophilic Addition to a Triple Bond |
94 |
26 |
4 |
4 |
100 |
| 13 | Nucleophilic Aliphatic Subsititution |
167 |
112 |
18 |
10 |
226 |
| 14 | Nucleophilic Aromatic Substitution |
29 |
25 |
7 |
5 |
43 |
| 15 | Phosphorylation |
63 |
65 |
6 |
6 |
116 |
| 16 | Ring Opening |
32 |
24 |
13 |
6 |
41 |