| Protein Name |
Ubiquitin thioesterase OTUB2 |
| #PDB ID |
12
|
| Organism |
Homo sapiens (Human) |
| Uniprot ID/ACC |
Q96DC9 (OTUB2_HUMAN)
|
| Synonym(s) |
- OTU domain
- ubiquitin aldehyde binding 2
- OTU domain-containing ubiquitin aldehyde-binding protein 2
- deubiquitinating enzyme OTUB2
- otubain-2
- ubiquitin-specific protease otubain 2
- ubiquitin-specific-processing protease OTUB2
- C14orf137
- OTB2
- OTU2
show 9 synonym(s)
|
| Gene Symbol |
OTUB2
|
| Gene ID |
78990
|
| Sequence |
MSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAIRKTKGDGNCFYRALGYSYLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDGSVSSLLKVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATECDHIQITALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAADKH |
| Protein Class |
HYDROLASE |
| Function |
Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'-linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.
|
