Covpdb











Protein
Protein Name D-alanyl-D-alanine carboxypeptidase
#PDB ID 11
Organism Streptomyces sp. (strain R61)
Uniprot ID/ACC P15555 (DAC_STRSR)
Synonym(s) -
Gene Symbol -
Gene ID -
Sequence MVSGTVGRGTALGAVLLALLAVPAQAGTAAAADLPAPDDTGLQAVLHTALSQGAPGAMVRVDDNGTIHQLSEGVADRATGRAITTTDRFRVGSVTKSFSAVVLLQLVDEGKLDLDASVNTYLPGLLPDDRITVRQVMSHRSGLYDYTNDMFAQTVPGFESVRNKVFSYQDLITLSLKHGVTNAPGAAYSYSNTNFVVAGMLIEKLTGHSVATEYQNRIFTPLNLTDTFYVHPDTVIPGTHANGYLTPDEAGGALVDSTEQTVSWAQSAGAVISSTQDLDTFFSALMSGQLMSAAQLAQMQQWTTVNSTQGYGLGLRRRDLSCGISVYGHTGTVQGYYTYAFASKDGKRSVTALANTSNNVNVLNTMARTLESAFCGKPTTAKLRSATSSATTVERHEDIAPGIARD
Protein Class HYDROLASE
Function Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e. a D-alanyl-D-alanine-terminated peptide), it becomes immobilized in the form of a long-lived, serine-ester-linked acyl enzyme and thus behave as penicillin-binding protein (PBP).
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB1277 RE1 1MPL Ki : 0.17 nM, Ki : 170000 nM PDBBind SHOW
COVPDB633 CEH 1HVB
-
-
SHOW
COVPDB632 CEF 1CEF
-
-
SHOW
COVPDB1232 PNM 1PWC
-
-
SHOW
COVPDB886 H2A 1PW8
-
-
SHOW
COVPDB152 2PB 1SDE
-
-
SHOW
COVPDB32 0MU 1PWD
-
-
SHOW
COVPDB647 CP5 1SCW
-
-
SHOW
COVPDB579 BSA 1YQS
-
-
SHOW
COVPDB435 CEP 1CEG
-
-
SHOW
COVPDB901 HE0 1PWG
-
-
SHOW