Protein Download |
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Protein Name | N-lysine methyltransferase SMYD2 | |||||
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#PDB ID | 7 | |||||
Organism | Homo sapiens | |||||
Uniprot ID/ACC | Q9NRG4 (SMYD2_HUMAN) | |||||
Protein Sequence | MRAEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH | |||||
Protein Class | TRANSCRIPTION REGULATOR | |||||
Synonym(s) |
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Gene Symbol | SMYD2 | |||||
Gene ID | 56950 | |||||
Pfam ID | PF00856, PF01753 | |||||
Interpro ID | IPR001214, IPR011990, IPR002893 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
3UJ | Small Molecule | 4WUY | IC50 : 15.0 nM, IC50 : 388.0 nM, IC50 : 600.0 nM, IC50 : 1000.0 nM | BindingDB | SHOW | |
3UJ | Small Molecule | 4WUY | IC50 : 15.0 nM | Binding MOAD | SHOW | |
I9H | Small Molecule | 5ARF | IC50 : 800.0 nM | Binding MOAD | SHOW | |
6T1 | Small Molecule | 5KJK | IC50 : 12.0 nM | Binding MOAD | SHOW | |
6TM | Small Molecule | 5KJM | IC50 : 65.0 nM | Binding MOAD | SHOW | |
EW1 | Small Molecule | 6CBX |
- |
- |
SHOW | |
6TL | Small Molecule | 5KJN |
- |
- |
SHOW | |
EW4 | Small Molecule | 6CBY |
- |
- |
SHOW |