Protein

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Protein Name Gamma-butyrobetaine dioxygenase
#PDB ID 10
Organism Homo sapiens
Uniprot ID/ACC O75936 (BODG_HUMAN)
Protein Sequence MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVENGN
Protein Class OXIDOREDUCTASE
Synonym(s)
  •   gamma-butyrobetaine dioxygenase
  • butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
  • gamma-butyrobetaine,2-oxoglutarate dioxygenase 1
  • BBH
  • BBOX
  • G-BBH
  • gamma-BBH
show 6 synonym(s)
Gene Symbol BBOX1
Gene ID 8424
Pfam ID PF06155, PF02668
Interpro ID IPR012775, IPR010376, IPR038492, IPR042098, IPR003819
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
IVL Small Molecule 4BG1 IC50 : 490.0 nM Binding MOAD SHOW
RTK Small Molecule 4BGK IC50 : 520.0 nM Binding MOAD SHOW
DLT Small Molecule 4BGM IC50 : 610.0 nM Binding MOAD SHOW
MZT Small Molecule 4BHF Kd : 4100.0 nM Binding MOAD SHOW
RUJ Small Molecule 4BHI Kd : 9300.0 nM Binding MOAD SHOW
NM3 Small Molecule 4C5W IC50 : 3300.0 nM Binding MOAD SHOW
NM2 Small Molecule 3O2G
-
-
SHOW
REE Small Molecule 3MS5
-
-
SHOW
C2T Small Molecule 4BHG
-
-
SHOW
449 Small Molecule 4CWD
-
-
SHOW