Protein

Download

Protein Name N-lysine methyltransferase SMYD2
#PDB ID 7
Organism Homo sapiens
Uniprot ID/ACC Q9NRG4 (SMYD2_HUMAN)
Protein Sequence MRAEGLGGLERFCSPGKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRCKQAFYCNVECQKEDWPMHKLECSPMVVFGENWNPSETVRLTARILAKQKIHPERTPSEKLLAVKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHLGFPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRKLSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAIMEVAHGKDHPYISEIKQEIESH
Protein Class TRANSCRIPTION REGULATOR
Synonym(s)
  •   SET and MYND domain-containing protein 2
  • histone methyltransferase SMYD2
  • lysine N-methyltransferase 3C
  • zinc finger, MYND domain containing 14
  • HSKM-B
  • KMT3C
  • ZMYND14
show 6 synonym(s)
Gene Symbol SMYD2
Gene ID 56950
Pfam ID PF00856, PF01753
Interpro ID IPR001214, IPR011990, IPR002893
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
3UJ Small Molecule 4WUY IC50 : 15.0 nM, IC50 : 388.0 nM, IC50 : 600.0 nM, IC50 : 1000.0 nM BindingDB SHOW
3UJ Small Molecule 4WUY IC50 : 15.0 nM Binding MOAD SHOW
I9H Small Molecule 5ARF IC50 : 800.0 nM Binding MOAD SHOW
6T1 Small Molecule 5KJK IC50 : 12.0 nM Binding MOAD SHOW
6TM Small Molecule 5KJM IC50 : 65.0 nM Binding MOAD SHOW
EW1 Small Molecule 6CBX
-
-
SHOW
6TL Small Molecule 5KJN
-
-
SHOW
EW4 Small Molecule 6CBY
-
-
SHOW