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Protein Download |
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| Protein Name | Gag-Pol polyprotein | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 15 | |||||
| Organism | Human immunodeficiency virus type 1 group M subtype B | |||||
| Uniprot ID/ACC | P03366 (POL_HV1B1) | |||||
| Protein Sequence | MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNTATIMMQRGNFRNQRKMVKCFNCGKEGHTARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLREDLAFLQGKAREFSSEQTRANSPTISSEQTRANSPTRRELQVWGRDNNSPSEAGADRQGTVSFNFPQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNFPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNKGRQKVVPLTNTTNQKTELQAIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIRKILFLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSATVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRNPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED | |||||
| Protein Class | VIRAL PROTEIN | |||||
| Synonym(s) | - | |||||
| Gene Symbol | - | |||||
| Gene ID | - | |||||
| Pfam ID | PF00540, PF00607, PF00552, PF02022, PF00075, PF00665, PF00077, PF00078, PF06815, PF06817, PF00098 | |||||
| Interpro ID | IPR001969, IPR043502, IPR000721, IPR017856, IPR036862, IPR001037, IPR001584, IPR003308, IPR000071, IPR012344, IPR001995, IPR021109, IPR034170, IPR018061, IPR008916, IPR008919, IPR010999, IPR043128, IPR012337, IPR002156, IPR036397, IPR000477, IPR010659, IPR010661, IPR001878, IPR036875 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| PNU | Small Molecule | 1IKX | IC50 : 17.0 nM, IC50 : 39.0 nM, IC50 : 77.0 nM, IC50 : 20.0 nM, IC50 : 22.0 nM, IC50 : 44.0 nM, IC50 : 179.0 nM, IC50 : 360.0 nM, IC50 : 24.0 nM, IC50 : 55.0 nM | BindingDB |  |
SHOW |
| PNU | Small Molecule | 1IKX | IC50 : 7.0 nM | PDBBind | |
SHOW |
| H9Y | Small Molecule | 6DTW |
- |
- |
 |
SHOW |
| ADB | Small Molecule | 1S9E |
- |
- |
 |
SHOW |
| 7AY | Small Molecule | 6X4A |
- |
- |
 |
SHOW |
| UO4 | Small Molecule | 6X4D |
- |
- |
 |
SHOW |
| 7N1 | Small Molecule | 5TW3 |
- |
- |
 |
SHOW |
| QAG | Small Molecule | 6UL5 |
- |
- |
 |
SHOW |
| UMY | Small Molecule | 6X4B |
- |
- |
 |
SHOW |
| UMV | Small Molecule | 6X4E |
- |
- |
 |
SHOW |
| TPB | Small Molecule | 1S6Q |
- |
- |
 |
SHOW |
| 7AX | Small Molecule | 6X47 |
- |
- |
 |
SHOW |
| H9Y | Small Molecule | 6DTX |
- |
- |
|
SHOW |
| 7AX | Small Molecule | 6X49 |
- |
- |
|
SHOW |
| UNS | Small Molecule | 6X4C |
- |
- |
 |
SHOW |
| UMV | Small Molecule | 6X4F |
- |
- |
|
SHOW |