| Protein Name |
Cathepsin B |
| #PDB ID |
11
|
| Organism |
Bos taurus (Bovine) |
| Uniprot ID/ACC |
P07688 (CATB_BOVIN)
|
| Synonym(s) |
show 1 synonym(s)
|
| Gene Symbol |
CTSB
|
| Gene ID |
281105
|
| Sequence |
MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMPCTHQY |
| Protein Class |
HYDROLASE |
| Function |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:1856234). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity).
|
