Protein
Protein Name L,D-transpeptidase 2
#PDB ID 15
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Uniprot ID/ACC I6Y9J2 (LDT2_MYCTU)
Synonym(s)
  •   L,D-transpeptidase LdtB
  • Rv2518c
show 1 synonym(s)
Gene Symbol ldtB
Gene ID 888160
Sequence MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA
Protein Class TRANSFERASE
Function Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap3-D-Ala4 bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap3 of the donor stem and the side chain of mDap3 of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems.
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB202 3V5 4QTF
-
-
SHOW
COVPDB251 58U 5DCC
-
-
SHOW
COVPDB1366 T8G 5E1G
-
-
SHOW
COVPDB724 DWZ 4QR7
-
-
SHOW
COVPDB303 6B7 5DZJ
-
-
SHOW
COVPDB268 DGF 5DUJ
-
-
SHOW
COVPDB89 2RG 6IYV
-
-
SHOW
COVPDB303 6B7 5DZP
-
-
SHOW
COVPDB251 58U 5DC2
-
-
SHOW
COVPDB1098 MNB 5LB1
-
-
SHOW
COVPDB942 IM2 6IYW
-
-
SHOW
COVPDB230 DRW 5DVP
-
-
SHOW
COVPDB304 6B8 5E1I
-
-
SHOW
COVPDB323 6QR 5K69
-
-
SHOW
COVPDB724 MXR 3VYP
-
-
SHOW