Protein |
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Protein Name | L,D-transpeptidase 2 | |||||
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#PDB ID | 15 | |||||
Organism | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||||
Uniprot ID/ACC | I6Y9J2 (LDT2_MYCTU) | |||||
Synonym(s) |
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Gene Symbol | ldtB | |||||
Gene ID | 888160 | |||||
Sequence | MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA | |||||
Protein Class | TRANSFERASE | |||||
Function | Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap3-D-Ala4 bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap3 of the donor stem and the side chain of mDap3 of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
COVPDB202 | 3V5 | 4QTF |
- |
- |
SHOW | |
COVPDB251 | 58U | 5DCC |
- |
- |
SHOW | |
COVPDB1366 | T8G | 5E1G |
- |
- |
SHOW | |
COVPDB724 | DWZ | 4QR7 |
- |
- |
SHOW | |
COVPDB303 | 6B7 | 5DZJ |
- |
- |
SHOW | |
COVPDB268 | DGF | 5DUJ |
- |
- |
SHOW | |
COVPDB89 | 2RG | 6IYV |
- |
- |
SHOW | |
COVPDB303 | 6B7 | 5DZP |
- |
- |
SHOW | |
COVPDB251 | 58U | 5DC2 |
- |
- |
SHOW | |
COVPDB1098 | MNB | 5LB1 |
- |
- |
SHOW | |
COVPDB942 | IM2 | 6IYW |
- |
- |
SHOW | |
COVPDB230 | DRW | 5DVP |
- |
- |
SHOW | |
COVPDB304 | 6B8 | 5E1I |
- |
- |
SHOW | |
COVPDB323 | 6QR | 5K69 |
- |
- |
SHOW | |
COVPDB724 | MXR | 3VYP |
- |
- |
SHOW |