Protein

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Protein Name Prothrombin
#PDB ID 4
Organism Homo sapiens
Uniprot ID/ACC P00734 (THRB_HUMAN)
Protein Sequence MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Protein Class HYDROLASE
Synonym(s)
  •   prothrombin
  • prepro-coagulation factor II
  • prothrombin B-chain
  • thrombin factor II
  • PT
  • RPRGL2
  • THPH1
show 6 synonym(s)
Gene Symbol F2
Gene ID 2147
Pfam ID PF00594, PF00051, PF09396, PF00089
Interpro ID IPR035972, IPR000294, IPR000001, IPR013806, IPR018056, IPR038178, IPR009003, IPR043504, IPR001314, IPR003966, IPR018992, IPR037111, IPR001254, IPR018114, IPR033116
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
MIU Small Molecule 1W7G Ki : 8000.0 nM PDBBind SHOW
MIU Small Molecule 1W7G Ki : 1900.0 nM BindingDB SHOW
MIU Small Molecule 1W7G Ki : 13000.0 nM Binding MOAD SHOW
7R9 Small Molecule 4LXB IC50 : 7.0 nM Binding MOAD SHOW
6XS Small Molecule 4LOY
-
-
SHOW
MRQ Small Molecule 6T7H
-
-
SHOW