Protein

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Protein Name Eukaryotic translation initiation factor 4E
#PDB ID 18
Organism Mus musculus
Uniprot ID/ACC P63073 (IF4E_MOUSE)
Protein Sequence MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
Protein Class TRANSLATION REGULATOR
Synonym(s)
  •   eukaryotic translation initiation factor 4E
  • eIF-4F 25 kDa subunit
  • mRNA cap-binding protein
  • EG668879
  • Eif4e-ps
  • If4
  • If4e
  • eIF-4
  • eIF-4E
show 8 synonym(s)
Gene Symbol Eif4e
Gene ID 13684
Pfam ID PF01652
Interpro ID IPR023398, IPR001040, IPR019770
Bound Ligands
HET ID Ligand Type PDB ID Binding Affinity Binding Database Structure Complex Card
MGP Small Molecule 1L8B Kd : 10.0 nM, Kd : 28.0 nM, Kd : 5720.0 nM, Kd : 2360.0 nM BindingDB SHOW
MGP Small Molecule 1L8B Kd : 140.0 nM Binding MOAD SHOW
MGP Small Molecule 5BXV Kd : 10.0 nM, Kd : 28.0 nM, Kd : 5720.0 nM, Kd : 2360.0 nM BindingDB SHOW
AKW Small Molecule 5OSX IC50 : 285.0 nM Binding MOAD SHOW
7LO Small Molecule 5M7Z
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-
SHOW
YDZ Small Molecule 5M83
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-
SHOW
OYW Small Molecule 6YLV
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-
SHOW
WZO Small Molecule 5M7V
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-
SHOW
G0Z Small Molecule 6GKL
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-
SHOW
M7G Small Molecule 1EJ1
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-
SHOW
MGP Small Molecule 6GKJ
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-
SHOW
6G0 Small Molecule 5J5O
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SHOW
RSE Small Molecule 5M7X
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SHOW
WZO Small Molecule 5M7W
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-
SHOW
WZO Small Molecule 6GKK
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SHOW
OYE Small Molecule 6YLR
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-
SHOW
YDZ Small Molecule 5M84
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SHOW
M7G Small Molecule 1EJH
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SHOW
M7G Small Molecule 1EJ4
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SHOW