Protein Download |
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Protein Name | Eukaryotic translation initiation factor 4E | |||||
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#PDB ID | 12 | |||||
Organism | Homo sapiens | |||||
Uniprot ID/ACC | P06730 (IF4E_HUMAN) | |||||
Protein Sequence | MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV | |||||
Protein Class | TRANSLATION REGULATOR | |||||
Synonym(s) |
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Gene Symbol | EIF4E | |||||
Gene ID | 1977 | |||||
Pfam ID | PF01652 | |||||
Interpro ID | IPR023398, IPR001040, IPR019770 |
Bound Ligands |
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
MGP | Small Molecule | 1IPC | Kd : 10.0 nM, Kd : 28.0 nM, Kd : 2360.0 nM, Kd : 5720.0 nM | BindingDB | SHOW | |
MGQ | Small Molecule | 2V8X | Kd : 790.0 nM, Kd : 1320.0 nM, Kd : 15500.0 nM, Kd : 26800.0 nM | BindingDB | SHOW | |
MGQ | Small Molecule | 2V8X | Kd : 6950.0 nM | Binding MOAD | SHOW | |
MGP | Small Molecule | 3AM7 | Kd : 10.0 nM, Kd : 28.0 nM, Kd : 2360.0 nM, IC50 : 5720.0 nM | BindingDB | SHOW | |
MGV | Small Molecule | 2V8Y | Kd : 7510.0 nM, Kd : 8220.0 nM | BindingDB | SHOW | |
MGV | Small Molecule | 2V8Y | Kd : 1960.0 nM | Binding MOAD | SHOW | |
MGP | Small Molecule | 5T46 | Kd : 10.0 nM, Kd : 28.0 nM, Kd : 5720.0 nM, Kd : 2360.0 nM | BindingDB | SHOW | |
MGO | Small Molecule | 2W97 | Kd : 9.0 nM | Binding MOAD | SHOW | |
MGP | Small Molecule | 4TPW | Ki : 28.0 nM, IC50 : 2360.0 nM, Kd : 10.0 nM, IC50 : 5720.0 nM | BindingDB | SHOW | |
M7G | Small Molecule | 4TQC |
- |
- |
SHOW | |
MGO | Small Molecule | 4AZA |
- |
- |
SHOW | |
6G6 | Small Molecule | 5J5Y |
- |
- |
SHOW | |
GTA | Small Molecule | 1IPB |
- |
- |
SHOW | |
MGT | Small Molecule | 5ZK7 |
- |
- |
SHOW |