| Protein Name |
Putative 2-dehydro-3-deoxy-D-gluconate aldolase YagE |
| #PDB ID |
3
|
| Organism |
Escherichia coli (strain K12) |
| Uniprot ID/ACC |
P75682 (YAGE_ECOLI)
|
| Synonym(s) |
- CP4-6 prophage
- putative 2-dehydro-3-deoxygluconate aldolase
- b0268
- ECK0269
show 3 synonym(s)
|
| Gene Symbol |
yagE
|
| Gene ID |
944925
|
| Sequence |
MPQSALFTGIIPPVSTIFTADGQLDKPGTAALIDDLIKAGVDGLFFLGSGGEFSQLGAEERKAIARFAIDHVDRRVPVLIGTGGTNARETIELSQHAQQAGADGIVVINPYYWKVSEANLIRYFEQVADSVTLPVMLYNFPALTGQDLTPALVKTLADSRSNIIGIKDTIDSVAHLRSMIHTVKGAHPHFTVLCGYDDHLFNTLLLGGDGAISASGNFAPQVSVNLLKAWRDGDVAKAAGYHQTLLQIPQMYQLDTPFVNVIKEAIVLCGRPVSTHVLPPASPLDEPRKAQLKTLLQQLKLC |
| Protein Class |
LYASE |
| Function |
Catalyzes the formation of 2-keto-3-deoxy-gluconate (KDG) from pyruvate and glyceraldehyde (PubMed:21294156). May also function as a 2-dehydro-3-deoxy-D-pentonate aldolase (PubMed:23233208). Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin (PubMed:21294156).
|
