| Protein Name |
Nuclear receptor subfamily 4 group A member 2 |
| #PDB ID |
2
|
| Organism |
Homo sapiens (Human) |
| Uniprot ID/ACC |
P43354 (NR4A2_HUMAN)
|
| Synonym(s) |
- NGFI-B/nur77 beta-type transcription factor homolog
- T-cell nuclear receptor NOT
- immediate-early response protein NOT
- intermediate-early receptor protein
- nuclear receptor related 1
- nur related protein-1
- human homolog of
- orphan nuclear receptor NR4A2
- orphan nuclear receptor NURR1
- transcriptionally inducible nuclear receptor related 1
- transcriptionally-inducible nuclear receptor
- HZF-3
- NOT
- NURR1
- RNR1
- TINUR
show 15 synonym(s)
|
| Gene Symbol |
NR4A2
|
| Gene ID |
4929
|
| Sequence |
MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSVYYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQSPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF |
| Protein Class |
TRANSCRIPTION REGULATOR |
| Function |
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).
|
