| Protein Name |
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 |
| #PDB ID |
9
|
| Organism |
Homo sapiens (Human) |
| Uniprot ID/ACC |
P28907 (CD38_HUMAN)
|
| Synonym(s) |
- 2'-phospho-ADP-ribosyl cyclase
- 2'-phospho-cyclic-ADP-ribose transferase
- ADP-ribosyl cyclase 1
- CD38 antigen (p45)
- NAD(+) nucleosidase
- cluster of differentiation 38
- cyclic ADP-ribose hydrolase 1
- ecto-nicotinamide adenine dinucleotide glycohydrolase
- ADPRC 1
- ADPRC1
show 9 synonym(s)
|
| Gene Symbol |
CD38
|
| Gene ID |
952
|
| Sequence |
MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI |
| Protein Class |
HYDROLASE |
| Function |
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
|
