Ligand
Ligand Name:   Cefuroxime
Ligand Type:   non-polymer
Ligand ID:   COVPDB635 PubChem:   5479529
Synonym(s):  
  •   cephuroxime
  • cefuroxim
  • cefuroximo
  • 55268-75-2
  • cefuroximum
  • zinacef danmark
  • zinacef
  • sharox
  • cefuroximum [inn-latin]
  • cefuroximo [inn-spanish]
  • unii-o1r9fj93ed
  • o1r9fj93ed
  • chebi:3515
  • (6r,7r)-3-(carbamoyloxymethyl)-7-[[(2z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • biofuroksym
  • cefuril
  • kefurox
  • q63409033
  • (6r,7r)-3-[(carbamoyloxy)methyl]-7-{[(2z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • cefuroxime [usan:inn:ban]
  • c16h16n4o8s
  • (6r,7r)-3-[(carbamoyloxy)methyl]-7-[(2z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6r,7r)-3-[(carbamoyloxy)methyl]-7-{[(2z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • einecs 259-560-1
  • brn 5783190
  • cefuroximine
  • cefuroxime [usan:ban:inn]
  • 4kov
  • cefuroxime (tn)
  • cefuroxime (usan/inn)
  • prestwick3_000720
  • chembl1436
  • bspbio_000939
  • (6r,7r)-7-(2-(2-furyl)glyoxylamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid 7(sup 2)-(z)-(o-methyloxime) carbamate (ester)
  • 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)acetyl)amino)-8-oxo-, (6r-(6alpha,7beta(z)))-
  • bidd:gt0619
  • bpbio1_001033
  • schembl1821942
  • hy-b1256a
  • zinc3830485
  • bdbm50422689
  • mfcd00864889
  • akos015962849
  • ac-4539
  • db01112
  • ks-5162
  • p802
  • ab0010602
  • cs-0013520
  • en300-53016
  • c06894
  • cefuroxime, vetranal(tm), analytical standard
  • d00262
  • 268c752
  • a830563
  • cefuroxime, antibiotic for culture media use only
  • w-105575
  • brd-k02733959-236-02-8
  • brd-k02733959-236-07-7
  • (6r,7r)-3-((carbamoyloxy)methyl)-7-((z)-2-(furan-2-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6r,7r)-3-(aminocarbonyloxymethyl)-7-[[(2z)-2-(furan-2-yl)-2-methoxyimino-ethanoyl]amino]-8-oxidanylidene-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6r,7r)-3-(carbamoyloxymethyl)-7-[[(2z)-2-(2-furanyl)-2-methoxyimino-1-oxoethyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6r,7r)-3-(carbamoyloxymethyl)-7-[[(2z)-2-(2-furyl)-2-methoxyimino-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6r,7r)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid
  • 3-[(carbamoyloxy)methyl]-7beta-[(2z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid
  • kef
  • kov
show 66 synonym(s)
DrugBank:   DB01112 ChEMBL:   CHEMBL1436
Canonical SMILES:   CO\N=C(\C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1
Standard InChI:   InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9+/t10-,14-/m1/s1
Molecular Formula:   C16H16N4O8S Mol. Weight:   424.06888 logP:   -0.536
HBD:   3 HBA:   9
#Rotatable Bonds:   7 TPSA:   173.76

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Lmo2812 protein Q8Y3M3 (Q8Y3M3_LISMO) Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 5ZQE CES
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SHOW
Beta-lactamase P9WKD3 (BLAC_MYCTU) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 3NBL DXF
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SHOW
DD-transpeptidase Q8Y547 (Q8Y547_LISMO) Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 3ZG9 DXF
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SHOW