Covpdb









Ligand
Ligand Name:   L-Pyroglutamylglycyl-L-arginine-p-nitroanilide
Ligand Type:   peptide-like
Ligand ID:   COVPDB388 PubChem:   121898
Synonym(s):  
  •   chromogenic substrate s-2444
  • 74661-31-7
  • s-2444
  • opgan
  • 5-oxo-prolyl-glycyl-arginine-4-nitroanilide
  • 5-oxo-pro-gly-arg-4-nitroanilide
  • pyr-gly-arg-pna
  • 5-oxo-l-prolylglycyl-l-arginine 4-nitroanilide
  • pyroglu-gly-arg-p-nitroanilide
  • schembl6171515
  • bdbm14716
  • dtxsid20996178
  • zinc13508293
  • (2s)-n-[2-[[(2s)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-5-oxopyrrolidine-2-carboxamide
  • l-argininamide, 5-oxo-l-prolylglycyl-n-(4-nitrophenyl)-
  • l-pyroglutamyl-glycyl-l-argininep-nitroaniline hydrochloride
  • (2s)-5-carbamimidamido-n-(4-nitrophenyl)-2-(2-{[(2s)-5-oxopyrrolidin-2-yl]formamido}acetamido)pentanamide hydrochloride
  • (s)-n-(2-((s)-5-guanidino-1-(4-nitrophenylamino)-1-oxopentan-2-ylamino)-2-oxoethyl)-5-oxopyrrolidine-2-carboxamide
  • n-(2-{[5-carbamimidamido-1-(4-nitroanilino)-1-oxopentan-2-yl]imino}-2-hydroxyethyl)-5-hydroxy-3,4-dihydro-2h-pyrrole-2-carboximidic acid
show 18 synonym(s)
DrugBank:   - ChEMBL:   -
Canonical SMILES:   NC(=N)NCCC[C@H](NC(=O)CNC(=O)[C@@H]1CCC(=O)N1)C(=O)Nc1ccc(cc1)[N+]([O-])=O
Standard InChI:   InChI=1S/C19H26N8O6/c20-19(21)22-9-1-2-13(18(31)24-11-3-5-12(6-4-11)27(32)33)26-16(29)10-23-17(30)14-7-8-15(28)25-14/h3-6,13-14H,1-2,7-10H2,(H,23,30)(H,24,31)(H,25,28)(H,26,29)(H4,20,21,22)/t13-,14-/m0/s1
Molecular Formula:   C19H26N8O6 Mol. Weight:   462.19754 logP:   -1.32383
HBD:   7 HBA:   7
#Rotatable Bonds:   11 TPSA:   221.44

Bound Proteins
Protein Name Uniprot ID/ACC Organism PDB ID HET Code Binding Affinity Binding Database Complex Card
Urokinase-type plasminogen activator P00749 (UROK_HUMAN) Homo sapiens (Human) 5WXS 7YF
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