Protein Download |
||
Protein Name | Poly [ADP-ribose] polymerase 1 | |
---|---|---|
#PDB ID | 3 | |
Organism | Homo sapiens | |
Uniprot ID/ACC | P09874 (PARP1_HUMAN) | |
Protein Sequence | MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW | |
Protein Class | TRANSCRIPTION REGULATOR | |
Synonym(s) |
|
|
Gene Symbol | PARP1 | |
Gene ID | 142 | |
Pfam ID | PF00533, PF08063, PF00644, PF02877, PF05406, PF00645 | |
Interpro ID | IPR001357, IPR036420, IPR012982, IPR038650, IPR008288, IPR012317, IPR004102, IPR036616, IPR036930, IPR008893, IPR001510, IPR036957 |
Bound Ligands |
||||||
HET ID | Ligand Type | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
15S | Small Molecule | 4HHZ | IC50 : 19.0 nM | PDBBind | SHOW | |
AAI | Small Molecule | 2RCW | Ki : 8.0 nM, EC50 : 3.0 nM | BindingDB | SHOW | |
UHB | Small Molecule | 6VKQ |
- |
- |
SHOW |