Protein
Protein Name Lysophospholipase-like protein 1
#PDB ID 1
Organism Homo sapiens (Human)
Uniprot ID/ACC Q5VWZ2 (LYPL1_HUMAN)
Synonym(s)
  •   Q96AV0
Gene Symbol LYPLAL1
Gene ID 127018
Sequence MAAASGSVLQRCIVSPAGRHSASLIFLHGSGDSGQGLRMWIKQVLNQDLTFQHIKIIYPTAPPRSYTPMKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGGFSMGGCMAIHLAYRNHQDVAGVFALSSFLNKASAVYQALQKSNGVLPELFQCHGTADELVLHSWAEETNSMLKSLGVTTKFHSFPNVYHELSKTELDILKLWILTKLPGEMEKQK
Protein Class HYDROLASE
Function Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site.
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB333 6WG 5KRE IC50 : 59 nM PDBBind SHOW