Protein
Protein Name Alpha-mannosidase 2
#PDB ID 4
Organism Drosophila melanogaster (Fruit fly)
Uniprot ID/ACC Q24451 (MAN2_DROME)
Synonym(s)
  •   alpha-Mannosidase class II a
  • CG18802-PA
  • CG18802-PB
  • alpha mannosidase II
  • alpha-Man-IIa-PA
  • alpha-Man-IIa-PB
  • alpha-mannosidase II
  • alpha-mannosidase-II
  • chain A
  • golgi Alpha-Mannosidase Ii
  • golgi Man II
  • golgi alpha-mannosidase
  • golgi mannosidase II
  • mannosidase II
  • Dmel_CG18802
  • CG18474
  • CG18802
  • CG8139
  • DM-GII.1
  • Dmel\CG18802
  • GMII
  • MAN-2
  • Man
  • Man-II
  • alpha-Man-II
  • alpha-Man-IIalpha
  • dGMII
  • dGMIIb
show 27 synonym(s)
Gene Symbol alphaManIIa
Gene ID 41126
Sequence MLRIRRRFALVICSGCLLVFLSLYIILNFAAPAATQIKPNYENIENKLHELENGLQEHGEEMRNLRARLAETSNRDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIYRLVLEKVNNCVRPSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS
Protein Class HYDROLASE
Function Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB804 FMF 1QX1 Ki : 7500000 nM PDBBind SHOW
COVPDB878 GUL 1QWU Ki : 600000 nM PDBBind SHOW
COVPDB1030 KGH 6RQZ
-
-
SHOW
COVPDB878 GUL 1QWN
-
-
SHOW