| Protein Name |
Prostasin |
| #PDB ID |
4
|
| Organism |
Homo sapiens (Human) |
| Uniprot ID/ACC |
Q16651 (PRSS8_HUMAN)
|
| Synonym(s) |
- channel-activating protease 1
- channel-activating serine protease 1
- protease
- serine 8
- CAP1
show 4 synonym(s)
|
| Gene Symbol |
PRSS8
|
| Gene ID |
5652
|
| Sequence |
MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVVPQTQESQPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH |
| Protein Class |
HYDROLASE |
| Function |
Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
|
