Protein |
||||||
| Protein Name | Methionine aminopeptidase 1 | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 4 | |||||
| Organism | Homo sapiens (Human) | |||||
| Uniprot ID/ACC | P53582 (MAP11_HUMAN) | |||||
| Synonym(s) |
|
|||||
| Gene Symbol | METAP1 | |||||
| Gene ID | 23173 | |||||
| Sequence | MAAVETRVCETDGCSSEAKLQCPTCIKLGIQGSYFCSQECFKGSWATHKLLHKKAKDEKAKREVSSWTVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMSQF | |||||
| Protein Class | HYDROLASE | |||||
| Function | Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle. |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| COVPDB1389 | TN4 | 5YR6 |
- |
- |
 |
SHOW |
| COVPDB1197 | OVA | 5YR5 |
- |
- |
 |
SHOW |
| COVPDB1389 | TN4 | 5YR4 |
- |
- |
|
SHOW |
| COVPDB1197 | OVA | 5YKP |
- |
- |
|
SHOW |