Protein
Protein Name Deaminated glutathione amidase
#PDB ID 2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Uniprot ID/ACC P47016 (NIT2_YEAST)
Synonym(s)
  •   putative hydrolase
  • YJL126W
show 1 synonym(s)
Gene Symbol NIT2
Gene ID 853316
Sequence MTSKLKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH
Protein Class HYDROLASE
Function Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione (PubMed:28373563). Possesses amidase activity toward deaminated ophthalmate in vitro (PubMed:28373563).
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB1172 OAA 4HG5
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SHOW
COVPDB495 AKG 4HG3
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SHOW