Protein
Protein Name Uridine 5'-monophosphate synthase
#PDB ID 9
Organism Homo sapiens (Human)
Uniprot ID/ACC P11172 (UMPS_HUMAN)
Synonym(s)
  •   OMPdecase
  • OPRTase
  • UMP synthase
  • orotate phosphoribosyltransferase
  • orotidine 5'-phosphate decarboxylase
  • OPRT
show 5 synonym(s)
Gene Symbol UMPS
Gene ID 7372
Sequence MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV
Protein Class LYASE
Function -
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB263 5FU 3G3M Ki : 1100 nM PDBBind SHOW
COVPDB263 5FU 3G3M Ki : 98000 nM BindingDB SHOW
COVPDB263 5FU 3G3D Ki : 18200 nM PDBBind SHOW
COVPDB263 5FU 3G3D Ki : 98000 nM BindingDB SHOW
COVPDB1411 U5P 3EX3 IC50 : 36000 nM PDBBind SHOW
COVPDB1411 U5P 3EX6 Ki : 220000 nM PDBBind SHOW
COVPDB1411 U5P 2QCN IC50 : 10000 nM PDBBind SHOW
COVPDB1414 UEP 3EWU IC50 : 24000 nM PDBBind SHOW
COVPDB307 U1P 3EWW
-
-
SHOW
COVPDB1411 U5P 3BGJ
-
-
SHOW
COVPDB1416 UFT 3MO7
-
-
SHOW