Protein
Protein Name Deoxyribose-phosphate aldolase
#PDB ID 5
Organism Escherichia coli (strain K12)
Uniprot ID/ACC P0A6L0 (DEOC_ECOLI)
Synonym(s)
  •   b4381
  • ECK4373
  • dra
  • thyR
  • tlr
show 4 synonym(s)
Gene Symbol deoC
Gene ID 948902
Sequence MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
Protein Class LYASE
Function Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate (PubMed:11598300, PubMed:17905878, PubMed:6749498). Can also catalyze the double aldol condensation of three acetaldehyde molecules, leading to the formation of 2,4,6-trideoxyhexose (Ref. 5).
Bound Ligands
Ligand ID HET Code PDB ID Binding Affinity Binding Database Structure Complex Card
COVPDB587 BU2 5EKY
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-
SHOW
COVPDB74 1BO 5EL1
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-
SHOW
COVPDB916 HPD 1JCL
-
-
SHOW
COVPDB916 HPD 1JCJ
-
-
SHOW
COVPDB74 1BO 5EMU
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SHOW