Protein |
||||||
| Protein Name | Thymidylate synthase | |||||
|---|---|---|---|---|---|---|
| #PDB ID | 2 | |||||
| Organism | Mus musculus (Mouse) | |||||
| Uniprot ID/ACC | P07607 (TYSY_MOUSE) | |||||
| Synonym(s) |
|
|||||
| Gene Symbol | Tyms | |||||
| Gene ID | 22171 | |||||
| Sequence | MLVVGSELQSDAQQLSAEAPRHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV | |||||
| Protein Class | TRANSFERASE | |||||
| Function | Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. |
Bound Ligands |
Ligand ID | HET Code | PDB ID | Binding Affinity | Binding Database | Structure | Complex Card |
| COVPDB1415 | UFP | 5FCT | IC50 : 42 nM, IC50 : 10000 nM, Ki : 30 nM, IC50 : 8 nM, Ki : 10 nM, Ki : 20 nM, Ki : 14 nM, IC50 : 17 nM | BindingDB |  |
SHOW |
| COVPDB1147 | NOH | 4EZ8 |
- |
- |
 |
SHOW |